Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease BEFREE Polymorphism of SREBF1 gene rs11868035 may increase susceptibility to PD in the northeastern Chinese population, while variant of USP25 gene rs2823357 may have no association with susceptibility to PD in northeastern Chinese. 30231795 2019
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease BEFREE Recently, SNP rs11868035, located in an intron of the sterol regulatory element binding factor (SREBF1) gene, was found to be associated with Parkinson's disease (PD) in a large European population in a genome-wide association study. 29128630 2018
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease BEFREE However, with the recent identification of SREBF1 as a risk locus for sporadic PD, our findings suggest a common mechanistic link between autosomal recessive and sporadic PD, and underscore the importance of mitochondrial homeostasis. 24912190 2014
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease BEFREE We discovered two novel, genome-wide significant associations with PD-rs6812193 near SCARB2 (p = 7.6 × 10(-10), OR = 0.84) and rs11868035 near SREBF1/RAI1 (p = 5.6 × 10(-8), OR = 0.85)-both replicated in an independent cohort. 21738487 2011
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.140 GeneticVariation disease GWASCAT Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011