Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease GWASCAT Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry. 28076899 2017
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 Biomarker disease CTD_human A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2014
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease GWASCAT A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2014
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 Biomarker disease CTD_human Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. 24097067 2014
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease GWASCAT Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. 24097067 2014
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 Biomarker disease BEFREE STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling. 20535138 2010
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease BEFREE Taking into consideration that different autoimmune diseases may share some common pathogenetic pathways, we hypothesized that STAT4, a susceptibility gene found to be associated with increased risk for systemic lupus erythematosus, rheumatoid arthritis, type 1 diabetes, Sjögren's syndrome, Wegener's granulomatosis, Crohn's disease, and ulcerative colitis may also have a role in psoriasis. 19500629 2010
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease BEFREE Recently, several reports has documented that a STAT4 haplotype is associated with RA, SLE and Sjogren's syndrome. 19479340 2010
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 GeneticVariation disease LHGDN Single nucleotide polymorphisms in the STAT4 gene are associated with primary Sjogren's syndrome. 18273036 2008
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.450 AlteredExpression disease BEFREE STAT4, a transcription factor transmitting signals induced by several key cytokines, has recently been identified as a genetic risk factor for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren's disease (SD), thus indicating that multiple autoimmune diseases may share common biochemical pathways that lead to immune deregulation. 18703106 2008