TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Ulcerative Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.020 Biomarker disease BEFREE These results suggest that telomerase and ILK activation occurs during the later stages of carcinoma progression, whereas upregulation of survivin, c-MYB, and Tcf-4 is a feature of the early stage of development of neoplasia, and thus, they might serve as early indicators for UC-associated colorectal carcinogenesis. 20027603 2010
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.020 AlteredExpression disease BEFREE The levels of Tcf-4 mRNA were decreased in patients with ileal disease irrespective of degree of inflammation, but were not decreased in colonic CD or ulcerative colitis. 17709525 2007