Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
GWASCAT |
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
|
30529582 |
2019 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
GWASCAT |
GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
|
29471430 |
2018 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
GWASCAT |
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
|
26965516 |
2016 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
BEFREE |
The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.
|
25131200 |
2014 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
GWASCAT |
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
|
24836286 |
2014 |
Colorectal Neoplasms
|
0.490 |
Biomarker
|
group |
CTD_human |
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
|
24836286 |
2014 |
Colorectal Neoplasms
|
0.490 |
Biomarker
|
group |
CTD_human |
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
|
21892161 |
2011 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
LHGDN |
Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk.
|
18478343 |
2008 |
Colorectal Neoplasms
|
0.490 |
AlteredExpression
|
group |
LHGDN |
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.
|
18621708 |
2008 |
Colorectal Neoplasms
|
0.490 |
AlteredExpression
|
group |
LHGDN |
Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex.
|
17983804 |
2007 |
Colorectal Neoplasms
|
0.490 |
AlteredExpression
|
group |
BEFREE |
Accordingly, ICAT down-regulation was correlated with progastrin overexpression and Tcf-4 target gene activation in human colorectal tumors, and ICAT repression was detected in the colon epithelium of tumor-prone, progastrin-overexpressing mice.
|
17920061 |
2007 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
LHGDN |
TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription.
|
16547505 |
2006 |
Colorectal Neoplasms
|
0.490 |
Biomarker
|
group |
LHGDN |
Colorectal cancer and genetic alterations in the Wnt pathway.
|
17143297 |
2006 |
Colorectal Neoplasms
|
0.490 |
GeneticVariation
|
group |
LHGDN |
Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.
|
11980438 |
2002 |
Colorectal Neoplasms
|
0.490 |
AlteredExpression
|
group |
BEFREE |
TCF-4 and beta-catenin form a transcription complex, which is important for both maintenance of normal epithelium and development of colorectal tumors.
|
12036905 |
2002 |