Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE Variants in the ZMIZ1 (rs12571751, p = 4.1 × 10(-5)) and TCF7L2 (rs7903146, p = 5.8 × 10(-4)) loci were strongly associated with LADA. 24906951 2015
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE The meta-analysis demonstrates that TCF7L2 rs7903146 polymorphism is a population-independent susceptibility locus for LADA in Europeans. 22109281 2012
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE TCF7L2 common genetic variants of susceptibility are associated only with low GADA antibody titre in LADA patients. 20546291 2011
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE Transcription factor 7-like 2-gene polymorphism is related to fasting C peptide in latent autoimmune diabetes in adults (LADA). 19533015 2010
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE However, and somewhat at odds with current thinking, TCF7L2, the most strongly associated gene with T2D to date, is strongly associated with LADA, a disorder considered by the World Health Organization to be a slowly progressing form of T1D. 20007922 2010
Latent autoimmune diabetes mellitus in adult
0.060 GeneticVariation disease BEFREE Notably, the frequency of the type 2 diabetes-associated CT/TT genotypes of rs7903146 in the TCF7L2 were increased in LADA subjects (52.8%; P = 0.03), to the same extent as in type 2 diabetic subjects (54.1%, P = 3 x 10(-7)), compared with control subjects (44.8%) and type 1 diabetic subjects (43.3%). 18310307 2008