Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
As cytology smears can be useful adjuncts in cytogenetic and molecular testing, we demonstrate TFE3 rearrangement by FISH analysis on cytologic smears in melanotic Xp11 translocation renal cancer.
|
29722173 |
2018 |
Renal carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Translocation renal cell carcinoma (tRCC) represents a rare subtype of kidney cancer associated with various <i>TFE3, TFEB</i>, or <i>MITF</i> gene fusions that are not responsive to standard treatments for RCC.
|
30061365 |
2018 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The corresponding mesenchymal neoplasms, including Xp11 neoplasm with melanocytic differentiation, TFE3 rearrangement-associated perivascular epithelioid cell tumor (PEComa) and melanotic Xp11 translocation renal cancer, can also harbor the identical gene fusion.
|
28315422 |
2017 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The first is a melanotic TFE3 translocation renal cancer with an indolent clinical course, occurring in a patient more than 3-decades older than the usual average age in which such tumors have been described.
|
28969862 |
2017 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In summary, we describe here for the first time the miRNA expression profiles of a molecularly distinct type of renal cancer associated with Xp11.2 translocations involving the TFE3 gene.
|
28411178 |
2017 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Regarding translocation renal cell carcinoma (RCC), TFE3, TFEB and ALK protein expression is crucial in establishing the diagnosis of Xp11.2 RCC, renal carcinoma with t(6;11)(p21;q12), and renal carcinoma with ALK rearrangement, respectively.
|
23957913 |
2013 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspect.
|
22207547 |
2012 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Sporadic, nonfamilial kidney cancer includes clear cell kidney cancer (75%), type 1 papillary kidney cancer (10%), papillary type 2 kidney cancer (including collecting duct and medullary RCC) (5%), the microphalmia-associated transcription (MiT) family translocation kidney cancers (TFE3, TFEB, and MITF), chromophobe kidney cancer (5%), and oncocytoma (5%).
|
23038766 |
2012 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Diagnostic pitfall on the histological spectrum of adult-onset renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.
|
20683695 |
2010 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The morphologic and immunohistochemical discrepancies between this intriguing melanotic tumor and other documented renal cell carcinomas bearing identical PSF-TFE3 gene fusion may suggest melanotic Xp11 translocation renal cancer is a distinct entity among the MiT/TFE family neoplasms.
|
19809274 |
2009 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion.
|
18358634 |
2008 |
Renal carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
A case of renal cancer with TFE3 gene fusion in an elderly man. Clinical, radiological and surgical findings.
|
17293662 |
2007 |
Renal carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Moreover, MITF and TFE3 reciprocally rescue one another in lines derived from CCS or pediatric renal carcinoma.
|
16766266 |
2006 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion.
|
15992428 |
2005 |
Renal carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
A unique case of renal carcinoma with Xp11.2 translocations/ TFE3 gene fusions in a 3-year-old child, with coexistent von Hippel-Lindau gene mutation.
|
15383938 |
2005 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Pediatric renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions and clinicopathologic associations.
|
15747097 |
2005 |
Renal carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We report the cloning of a novel clathrin heavy-chain gene (CLTC)-TFE3 gene fusion resulting from a t(X;17)(p11.2;q23) in a renal carcinoma arising in a 14-year-old boy.
|
12917640 |
2003 |
Renal carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
PRCC, the commonest TFE3 fusion partner in papillary renal carcinoma is associated with pre-mRNA splicing factors.
|
11313942 |
2001 |