Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE As cytology smears can be useful adjuncts in cytogenetic and molecular testing, we demonstrate TFE3 rearrangement by FISH analysis on cytologic smears in melanotic Xp11 translocation renal cancer. 29722173 2018
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 Biomarker disease BEFREE Translocation renal cell carcinoma (tRCC) represents a rare subtype of kidney cancer associated with various <i>TFE3, TFEB</i>, or <i>MITF</i> gene fusions that are not responsive to standard treatments for RCC. 30061365 2018
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE The corresponding mesenchymal neoplasms, including Xp11 neoplasm with melanocytic differentiation, TFE3 rearrangement-associated perivascular epithelioid cell tumor (PEComa) and melanotic Xp11 translocation renal cancer, can also harbor the identical gene fusion. 28315422 2017
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE The first is a melanotic TFE3 translocation renal cancer with an indolent clinical course, occurring in a patient more than 3-decades older than the usual average age in which such tumors have been described. 28969862 2017
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE In summary, we describe here for the first time the miRNA expression profiles of a molecularly distinct type of renal cancer associated with Xp11.2 translocations involving the TFE3 gene. 28411178 2017
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Regarding translocation renal cell carcinoma (RCC), TFE3, TFEB and ALK protein expression is crucial in establishing the diagnosis of Xp11.2 RCC, renal carcinoma with t(6;11)(p21;q12), and renal carcinoma with ALK rearrangement, respectively. 23957913 2013
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspect. 22207547 2012
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Sporadic, nonfamilial kidney cancer includes clear cell kidney cancer (75%), type 1 papillary kidney cancer (10%), papillary type 2 kidney cancer (including collecting duct and medullary RCC) (5%), the microphalmia-associated transcription (MiT) family translocation kidney cancers (TFE3, TFEB, and MITF), chromophobe kidney cancer (5%), and oncocytoma (5%). 23038766 2012
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Diagnostic pitfall on the histological spectrum of adult-onset renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions. 20683695 2010
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE The morphologic and immunohistochemical discrepancies between this intriguing melanotic tumor and other documented renal cell carcinomas bearing identical PSF-TFE3 gene fusion may suggest melanotic Xp11 translocation renal cancer is a distinct entity among the MiT/TFE family neoplasms. 19809274 2009
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion. 18358634 2008
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 Biomarker disease BEFREE A case of renal cancer with TFE3 gene fusion in an elderly man. Clinical, radiological and surgical findings. 17293662 2007
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 Biomarker disease BEFREE Moreover, MITF and TFE3 reciprocally rescue one another in lines derived from CCS or pediatric renal carcinoma. 16766266 2006
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion. 15992428 2005
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 Biomarker disease BEFREE A unique case of renal carcinoma with Xp11.2 translocations/ TFE3 gene fusions in a 3-year-old child, with coexistent von Hippel-Lindau gene mutation. 15383938 2005
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE Pediatric renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions and clinicopathologic associations. 15747097 2005
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 GeneticVariation disease BEFREE We report the cloning of a novel clathrin heavy-chain gene (CLTC)-TFE3 gene fusion resulting from a t(X;17)(p11.2;q23) in a renal carcinoma arising in a 14-year-old boy. 12917640 2003
CUI: C1378703
Disease: Renal carcinoma
Renal carcinoma
0.100 AlteredExpression disease BEFREE PRCC, the commonest TFE3 fusion partner in papillary renal carcinoma is associated with pre-mRNA splicing factors. 11313942 2001