TH, tyrosine hydroxylase, 7054

N. diseases: 321; N. variants: 71
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.320 Biomarker disease BEFREE The effects of two doses of filgrastim (20 and 40 μg/kg) on spontaneous locomotion, catalepsy, body weight, histology, and striatal dopamine (DA) content, as well as tyrosine hydroxylase (TH) and α-synuclein expression, were evaluated. 29327204 2018
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.320 Biomarker disease BEFREE Brain histology and immunochemistry (Nissl-staining, glial fibrillary acidic protein and tyrosine hydroxylase immunohistochemistry) and behavioral testing (catalepsy, akinesia, rotarod and swim test) showed that RP-loaded PLGA NPs were able to revert PD-like symptoms of neurodegeneration in the animal model assayed. 28782388 2017
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.320 Biomarker disease CTD_human Dopamine deficiency in mice. 10984662 2000
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.320 Biomarker disease CTD_human Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission. 9822156 1998