TH, tyrosine hydroxylase, 7054

N. diseases: 321; N. variants: 71
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease RGD The results indicate that there exists possible interrelation between TH and TPH gene expression and epigenetic histone acetylation in CUS-induced depressive rats, which at least partly contributes to the etiology of depression. 24495952 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease PSYGENET The results indicate that there exists possible interrelation between TH and TPH gene expression and epigenetic histone acetylation in CUS-induced depressive rats, which at least partly contributes to the etiology of depression. 24495952 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease PSYGENET Tyrosine-hydroxylase (TH) and dopamine-beta-hydroxylase (DBH) mRNA levels were decreased both in right and left atria, while phenylethanolamine N-methyltransferase (PNMT) mRNAs were increased in left atria and both ventricles of depression model rats. 23305027 2012
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease PSYGENET Polymorphisms of genes for brain-derived neurotrophic factor, methylenetetrahydrofolate reductase, tyrosine hydroxylase, and endothelial nitric oxide synthase in depression and metabolic syndrome. 20163778 2010
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease PSYGENET Elevated renal norepinephrine in proANP gene-disrupted mice is associated with increased tyrosine hydroxylase expression in sympathetic ganglia. 17482290 2007
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.500 Biomarker disease PSYGENET Overexpressed thioredoxin compensates Fanconi anemia related chromosomal instability. 11948424 2002