TH, tyrosine hydroxylase, 7054

N. diseases: 321; N. variants: 71
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1135161
Disease: Stage 4S neuroblastoma
Stage 4S neuroblastoma
0.030 AlteredExpression disease BEFREE High levels of TH and DCX mRNAs when detected in PB and BM at diagnosis independently predicted worse outcome in a cohort of 162 metastatic NB. 26498952 2016
CUI: C1135161
Disease: Stage 4S neuroblastoma
Stage 4S neuroblastoma
0.030 AlteredExpression disease BEFREE We conclude that high expression of TH and DDC both in PB and BM corresponds to metastatic neuroblastoma at diagnosis, residual disease, and poor outcome. 18814238 2008
CUI: C1135161
Disease: Stage 4S neuroblastoma
Stage 4S neuroblastoma
0.030 Biomarker disease BEFREE We used real-time quantitative reverse transcription-PCR (QPCR) of the tyrosine hydroxylase (TH), GD2 synthetase (GALGT), and embryonic lethal, abnormal vision, Drosophila-like 4 (ELAVL4) genes to detect disseminated neuroblastoma cells. 16384890 2006