Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 AlteredExpression disease BEFREE TLR-4 expression levels were higher in patients with ACS than in patients with stable angina. 25179298 2016
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 Biomarker disease CTD_human (1) Expressions of TLR4, levels of TNF-α and MMP-9 were increased and the rate was rising from the control group, to SAP group and then to ACS group. 20981132 2011
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 AlteredExpression disease BEFREE The TLR4 expression levels were significantly higher in the ACS group than in the SAP group. 19556696 2009
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 AlteredExpression disease BEFREE The results showed that the expression of TLR4 and MAPK families are increased in the patients with acute coronary syndrome (ACS), compared with it in the patients with stable angina and controls. 18373609 2008
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 AlteredExpression disease BEFREE Moreover, TLR4 expression levels in stable angina pectoris (SAP) patients were elevated compared with those in non-CAD subjects (P < 0.05), and those in acute coronary syndrome patients were higher than SAP patients even in low-hsCRP subjects (P < 0.01). 17045300 2007
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 Biomarker disease BEFREE Compared with serum from patients with UA and AMI, challenging TLR4-transfected CHO cells with serum from SA patients yielded only a weak response (P<0.0001). 15883205 2006
CUI: C0340288
Disease: Stable angina
Stable angina
0.360 GeneticVariation disease BEFREE The TLR4 399Ile allele had the greatest impact on ACS risk (uncorrected p = 0.006); however there was no evidence overall that the resistance alleles cumulatively influenced the risk of ACS compared to controls or stable angina patients (p = 0.12, and p = 0.40, respectively). 17044867 2006