Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 AlteredExpression disease BEFREE Toll-like receptor-4 is upregulated in plaque debris of patients with acute coronary syndrome more than Toll-like receptor-2. 25179298 2016
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 Biomarker disease CTD_human The study aims to explore the relationship between expressions of toll-like receptor 4 (TLR4) on peripheral blood monocytes, serum tumor necrosis factor-alpha (TNF-α) and matrix metalloproteinase-9 (MMP-9) in patients with acute coronary syndromes(ACS), and to investigate the possible mechanisms of Benazepril stabilizing atherosclerosis plaques. 20981132 2011
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 AlteredExpression disease BEFREE TLR4 expression control may be a novel target for ACS treatment. 19556696 2009
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 AlteredExpression disease BEFREE Moreover, TLR4 expression levels in stable angina pectoris (SAP) patients were elevated compared with those in non-CAD subjects (P < 0.05), and those in acute coronary syndrome patients were higher than SAP patients even in low-hsCRP subjects (P < 0.01). 17045300 2007
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 Biomarker disease BEFREE Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. 15883205 2006
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 GeneticVariation disease BEFREE These results, which must be confirmed by a prospective longitudinal study, provide evidence of an association between the Asp299Gly polymorphism of the human TLR4 receptor and acute coronary syndromes. 14563652 2004
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.350 GeneticVariation disease LHGDN The Asp299Gly polymorphism provides evidence of an association of the TLR4 receptor and acute coronary syndromes. 14563652 2004