TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Cardiac Arrest ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease BEFREE Inhibition of central IL-6 and TNF-α also decreased ASIC1 in the hippocampus of CA rats. 31272354 2019
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease BEFREE We observed amplification of IL-1β, IL-6 and TNF-α as well as 8-iso PGF2α and 8-OHdG in the hippocampus of CA rats. 31556851 2019
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease BEFREE The survival rate, neurological deficit score (NDS), and expression of TLR4, phosphorylated NF-κB and TNF-α in hippocampal tissues were evaluated at 72 h post-CA/CPR. 30953818 2019
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 AlteredExpression disease BEFREE Pro-inflammatory factor messenger RNA expression (TNF-α and IL-6), NFκβ activation, and SUR1-TRPM4 levels were upregulated after CA/CPR. 29150777 2018
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease BEFREE TNF-α immunoreactivity decreased significantly in neurons of the stratum pyramidale in the CA1 region 6 hours post-CA, decreased gradually until 1 day post-CA, and increased significantly again 2 days post-CA. 29323039 2017
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 AlteredExpression disease BEFREE The aim of this study was to evaluate the mRNA expression levels of the cytokines interferon (IFN-γ), tumor necrosis factor, interleukin (IL-1β, IL-17A, IL-10), receptor activator for nuclear factor kappa B ligand, and the chemokines CCL2/MCP-1 and CCL5 in the periapical interstitial fluid from SCA individuals compared with healthy individuals. 25576201 2015
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease BEFREE This study aimed to evaluate the profile of the proinflammatory cytokines interleukin-6, tumor necrosis factor-α, and interleukin-17 in patients with SCA and also to assess the haplotypes associated with beta globin cluster S (HBB(*)S). 24290434 2014
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 GeneticVariation disease BEFREE In the present study, we investigated the associations between Tumor Necrosis Factor-alpha (TNF-alpha) -308G>A and Interleukin 8 (IL-8) -251A>T gene polymorphisms, medical history and classical biomarkers in children with steady-state SCA. 21802960 2011
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 GeneticVariation disease BEFREE TNF-α (-308) polymorphism was determined in 49 adults with SCA. 21160173 2011
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease RGD Hypothermia after cardiac arrest does not alter serum inflammatory markers. 18679114 2008
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 GeneticVariation disease BEFREE Similar findings in 2 independent study populations strongly suggest that the TNF(-308) G/A promoter polymorphism is a clinically important risk factor for large vessel stroke in children with SCA. 17600229 2007
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.600 Biomarker disease CTD_human Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. 9806674 1998