C3AR1, complement C3a receptor 1, 719

N. diseases: 73; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker group BEFREE Thus, whilst the C3aR modulates some elements of disease pathogenesis, overall it is not critical in effector responses and glomerular injury caused by autoimmunity to MPO. 29315316 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker group BEFREE Complement 3a receptor (C3aR) and complement 5a receptor (C5aR) have been reported to be involved in T cell mediated autoimmune disease. 29138505 2017
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker group BEFREE Complement activation products C3a and C5a have broad pro-inflammatory potential through their receptors, C3aR and C5aR, and contribute to the pathogenesis of several inflammatory and autoimmune diseases, but their roles in IgAN are poorly defined. 24327134 2014