TTC4, tetratricopeptide repeat domain 4, 7268

N. diseases: 32; N. variants: 1
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease LHGDN We show that TTC4 protein levels are raised in malignant melanoma cell lines compared to melanocytes. 18320024 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.020 GeneticVariation disease BEFREE The gene was originally identified as being localized in a genomic region linked to breast cancer and subsequent studies on melanoma cell lines revealed point mutations in the TTC4 protein that may be associated with the progression of malignant melanoma. 18320024 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Our findings indicate that TTC4 may participate in the pathogenesis of malignant melanomas of the skin. 11126369 2000