TYMS, thymidylate synthetase, 7298

N. diseases: 406; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 GeneticVariation group LHGDN The polymorphisms of TS and MTHFR predict survival of gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy in Chinese population. 18704422 2009
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker group CTD_human Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer. 18652704 2008
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker group CTD_human Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis. 19020767 2008
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker group CTD_human Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. 18505590 2008
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 AlteredExpression group LHGDN Thymidylate synthase and thymidine phosphorylase gene expression as predictive parameters for the efficacy of 5-fluorouracil-based adjuvant chemotherapy for gastric cancer. 17854149 2007
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker group CTD_human Combined GADD45A and thymidine phosphorylase expression levels predict response and survival of neoadjuvant-treated gastric cancer patients. 15837757 2005
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 GeneticVariation group LHGDN Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis. 15930032 2005
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 AlteredExpression group LHGDN Significant increase in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate status. 15817609 2005
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 GeneticVariation group LHGDN Association of thymidylate synthase polymorphisms with gastric cancer susceptibility. 15386366 2004
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 GeneticVariation group LHGDN Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking. 15244514 2004
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 AlteredExpression group BEFREE Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. 7882343 1995