TYMS, thymidylate synthetase, 7298

N. diseases: 406; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 Biomarker group CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 Biomarker group CTD_human Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis. 19020767 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 GeneticVariation group LHGDN Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer. 17385677 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 GeneticVariation group LHGDN Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study. 17372271 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 Biomarker group CTD_human Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. 16723031 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group LHGDN Difference in Ki67 and thymidylate synthase expression in primary tumour compared with metastatic nodes in breast cancer patients. 17065089 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group LHGDN The prognostic significance of thymidine phosphorylase, thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in breast carcinomas. 14702180 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 GeneticVariation group LHGDN Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype. 15510613 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 Biomarker group BEFREE Therefore, a semiquantitative polymerase chain reaction (PCR) technique to measure TS RNA concentration in breast tumour cell lines has been developed with potential for measuring TS RNA levels in individual breast tumours. 8028610 1994