|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, VEGF-A expression correlates with clinical stages of osteosarcoma.
|
31719210 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study, a significant correlation was found between ADM and VEGF expression in the plasma of osteosarcoma patients.
|
30890367 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Chondrosarcoma, Ewing's Sarcoma and Osteosarcoma are the tumours of the musculoskeletal system in which the activity of VEGF has been closely studied.
|
31169001 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In summary, it was demonstrated that miRNA-638 expression change in patients with osteosarcoma and an <i>in vitro</i> model via PLD1 and VEGF expression and miRNA-638 may be potential clinical indicators of osteosarcoma.
|
30988774 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
This study aimed to investigate the expression levels of Caveolin-1 and VEGF in osteosarcoma and their associations with clinicopathological data.
|
31676993 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma.
|
31448053 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Amentoflavone significantly inhibits tumor growth and reduces protein levels of phospho-extracellular signal-regulated kinase (P-ERK), nuclear factor-kappaB (NF-κB) p65 (Ser536), vascular endothelial growth factor (VEGF), matrix metallopeptidase 9 (MMP-9), X-linked inhibitor of apoptosis protein (XIAP), and cyclin-D1 in osteosarcoma in vivo.
|
31262893 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
TfR1 and VEGF are potential prognostic factors for osteosarcoma.
|
31484533 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Simultaneous silencing of VEGF and Survivin using the dual siRNA may be an advantageous alternative for the development of therapeutic strategies against human osteosarcoma.
|
30566604 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells.
|
31180533 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we reported the higher expression of vascular endothelial growth factor‑A (VEGF‑A) in osteosarcoma cells that were resistant to anoikis than in parental osteosarcoma cells, promoting the proliferation, tube formation, and migration of human umbilical vein endothelial cells (HUVECs).
|
30542722 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Inhibition of VEGF may aid in treating osteosarcoma in clinic.
|
29257309 |
2018 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We identified 12 SNVs in CTLA-4, IL-8, MDM2, PRCKG, RECQL5, TNF-a, TP53, XRCC3, and VEGF that correlated with osteosarcoma susceptibility.
|
30235774 |
2018 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
However, the regulation of the VEGF/VEGFR1 expression is still unclear in OS.
|
29474747 |
2018 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Spearman's correlation analysis was utilized to examine the relationship between miR‑944 and VEGF expression levels, and rescue experiments were applied to further verify whether VEGF mediates the role of miR‑944 in OS.
|
30280196 |
2018 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Here, we screened an OS cell-specific aptamer (LC09) and developed a LC09-functionalized PEG-PEI-Cholesterol (PPC) lipopolymer encapsulating CRISPR/Cas9 plasmids encoding VEGFA gRNA and Cas9.
|
28938163 |
2017 |
|
Osteosarcoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The pooled results suggested that VEGF-2578C/A polymorphism was significantly associated with osteosarcoma risk in all genetic models as well as VEGF-634G/C polymorphism.
|
27144378 |
2017 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
It has been reported that VEGFR expression correlates with the outcome of patients with osteosarcoma and circulating VEGF level has been associated with the development of lung metastasis.
|
28656259 |
2017 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Cyr61 and VEGF expressions moderately correlated with each other in osteosarcoma, and exhibited significant association with Enneking stage and distant metastasis.
|
28647210 |
2017 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, we show that WISP-1 promotes VEGF-A expression in human osteosarcoma cells, subsequently inducing human endothelial progenitor cell (EPC) migration and tube formation.
|
28406476 |
2017 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We found that serum concentrations of CXCL8 and vascular endothelial growth factor were elevated in osteosarcoma patients in comparison with those in NCs.
|
28736978 |
2017 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
WWOX promoted apoptosis and inhibited invasion and expression of bcl-2, OPN, RUNX2, and VEGF in osteosarcoma cells <i>in vitro</i>.
|
28977834 |
2017 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Increased vascular endothelial growth factor (VEGF) expression in osteosarcoma correlates with a poor outcome.
|
28631382 |
2017 |
|
Osteosarcoma
|
0.400 |
PosttranslationalModification
|
disease |
BEFREE |
In vitro, depletion of SH3GL1 abrogates P130<sup>cas</sup> phosphorylation and IL-6- and VEGF-induced OS cell proliferation and migration.
|
28702842 |
2017 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This was associated with a decrease in VEGF (vascular endothelial growth factor) and SDF-1 (stromal derived factor-1) on the protein level, both related to the control of angiogenesis and furthermore discussed as crucial factors in osteosarcoma progression and metastasis.
|
28632184 |
2017 |