VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Disease: Retinal Vein Occlusion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE The intravitreous injection of therapeutic proteins that neutralize vascular endothelial growth factor (VEGF) family members is efficient to reduce macular edema associated with wet age-related macular degeneration (AMD), retinal vein occlusion (RVO) and diabetic retinopathy (DR). 31173913 2019
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE IMPACT OF RETINAL ISCHEMIA ON FUNCTIONAL AND ANATOMICAL OUTCOMES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY IN PATIENTS WITH RETINAL VEIN OCCLUSION. 31157714 2019
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE Association of Disorganization of Retinal Inner Layers With Visual Acuity Response to Anti-Vascular Endothelial Growth Factor Therapy for Macular Edema Secondary to Retinal Vein Occlusion. 30286219 2019
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE The top cited references mainly presented anti-VEGF medications on the management of RVO. 31528507 2019
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE Impact of Time to Anti-Vascular Endothelial Growth Factor Intervention on Visual Outcomes for Patients Diagnosed With Retinal Vein Occlusion. 30457641 2018
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE Longitudinal quantification of retinal nonperfusion (RNP) in eyes with retinal vein occlusion (RVO) undergoing anti-vascular endothelial growth factor therapy. 29664983 2018
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE Pathophysiological Role of VEGF on Retinal Edema and Nonperfused Areas in Mouse Eyes With Retinal Vein Occlusion. 30267092 2018
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE PurposeRanibizumab, an anti-vascular endothelial growth factor, and dexamethasone, a corticosteroid, have been shown to be effective in treating macular oedema secondary to retinal vein occlusion (RVO) (central RVO (CRVO) and branch RVO (BRVO)). 27911446 2017
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 AlteredExpression disease BEFREE In contrast, VEGF expression in the RVO + panretinal photocoagulation group was strongly suppressed in both the inner nuclear and ganglion cell layers on days 7 and 14. 29098298 2017
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE QUALITATIVE AND QUANTITATIVE FOLLOW-UP USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF RETINAL VEIN OCCLUSION TREATED WITH ANTI-VEGF: Optical Coherence Tomography Angiography Follow-up of Retinal Vein Occlusion. 27685676 2017
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE This study also identifies VEGFR1 and VCAM-1 as molecular targets whose suppression could supplement VEGF neutralization for treatment of RVO and diabetic retinopathy. 28931763 2017
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease BEFREE Comparison between anti-VEGF therapy and corticosteroid or laser therapy for macular oedema secondary to retinal vein occlusion: A meta-analysis. 28639290 2017
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease RGD Effects of intravitreal triamcinolone acetonide on retinal gene expression in a rat model of central retinal vein occlusion. 21487926 2011
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 AlteredExpression disease BEFREE Anti-angiogenic VEGF (vascular endothelial growth factor) isoforms, generated from differential splicing of exon 8, are widely expressed in normal human tissues but down-regulated in cancers and other pathologies associated with abnormal angiogenesis (cancer, diabetic retinopathy, retinal vein occlusion, the Denys-Drash syndrome and pre-eclampsia). 19909248 2009
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 AlteredExpression disease LHGDN Visual prognosis and vitreous cytokine levels after arteriovenous sheathotomy in branch retinal vein occlusion associated with macular oedema. 18039346 2008
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.600 Biomarker disease CTD_human Rapid regression of disc neovascularization in a patient with proliferative diabetic retinopathy following adjunctive intravitreal bevacizumab. 16680105 2006