Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.330 Biomarker group BEFREE Mixed-effect models were used to assess additive associations of 176 tag single-nucleotide polymorphisms (SNPs) in CACNA1A and CACNA1C with longitudinal BP changes and hypertension incidence. 27418245 2016
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.330 Biomarker group CTD_human Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. 22949532 2012
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.330 GeneticVariation group BEFREE Three SNPs in CACNA1D or CACNA1C are genetic polymorphisms conferring sensitivity to the antihypertensive effects of L-type dCCBs in patients with hypertension. 19225208 2009
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.330 GeneticVariation group BEFREE CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension. 16610939 2006