Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Conventional (Clear Cell) Renal Cell Carcinoma
0.040 AlteredExpression disease BEFREE Also, increases in LC3B and p62 expression suggest a blockage of the autophagic flux in RCC in response to 10b. 31260889 2019
Conventional (Clear Cell) Renal Cell Carcinoma
0.040 Biomarker disease BEFREE Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma. 30902965 2019
Conventional (Clear Cell) Renal Cell Carcinoma
0.040 Biomarker disease BEFREE Here we establish, using shRNAs, a dominant-negative mutant, and a pharmacologic inhibitor, mefenamic acid (MFA), that the Transient Receptor Potential Melastatin 3 (TRPM3) channel promotes the growth of clear cell renal cell carcinoma (ccRCC) and stimulates MAP1LC3A (LC3A) and MAP1LC3B (LC3B) autophagy. 25517751 2014
Conventional (Clear Cell) Renal Cell Carcinoma
0.040 Biomarker disease BEFREE VHL-regulated MiR-204 suppresses tumor growth through inhibition of LC3B-mediated autophagy in renal clear cell carcinoma. 22516261 2012