AXIN2, axin 2, 8313

N. diseases: 169; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Expanding the genotype-phenotype spectrum in hereditary colorectal cancer by gene panel testing. 27696107 2017
Oligodontia-Colorectal Cancer Syndrome
0.710 CausalMutation disease CLINVAR Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis. 27090353 2016
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Expression and localization of axin 2 in colorectal carcinoma and its clinical implication. 23702820 2013
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. 22745173 2012
Oligodontia-Colorectal Cancer Syndrome
0.710 CausalMutation disease CLINVAR Mutations in WNT10A are present in more than half of isolated hypodontia cases. 22581971 2012
Oligodontia-Colorectal Cancer Syndrome
0.710 GermlineCausalMutation disease ORPHANET AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. 21416598 2011
Oligodontia-Colorectal Cancer Syndrome
0.710 GeneticVariation disease CLINVAR AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. 21416598 2011
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. 21416598 2011
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability. 16247484 2006
Oligodontia-Colorectal Cancer Syndrome
0.710 GeneticVariation disease BEFREE Recently, germline mutations in the Wnt pathway component gene AXIN2 have been associated with tooth agenesis-colorectal cancer syndrome. 16941501 2006
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. 16815967 2006
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CLINGEN Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. 15042511 2004
Oligodontia-Colorectal Cancer Syndrome
0.710 GeneticVariation disease CLINVAR Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. 15042511 2004
Oligodontia-Colorectal Cancer Syndrome
0.710 GermlineCausalMutation disease ORPHANET Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. 15042511 2004
Oligodontia-Colorectal Cancer Syndrome
0.710 CausalMutation disease CLINVAR Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. 15042511 2004
Oligodontia-Colorectal Cancer Syndrome
0.710 Biomarker disease CTD_human