CASP3, caspase 3, 836

N. diseases: 819; N. variants: 26
Disease: Brain Ischemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 Biomarker disease BEFREE Tlr2 Deficiency is Associated with Enhanced Elements of Neuronal Repair and Caspase 3 Activation Following Brain Ischemia. 30808918 2019
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 Biomarker disease BEFREE This indicates no involvement of the BNIP3 gene along with the CASP3 gene in the CA3 region of the hippocampus in delayed neuronal death after brain ischemia. 31707369 2019
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 Biomarker disease BEFREE Nesfatin-1 significantly reduced caspase-3 (P < 0.01) and microglial activation (P < 0.01) and improved spatial memory impairments (P < 0.05) induced by brain ischemia. 29956089 2018
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 AlteredExpression disease LHGDN Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia. 12605885 2003
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.340 Biomarker disease CTD_human Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. 11756504 2002