CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer
0.020 PosttranslationalModification disease BEFREE Hemimethylation of the CASPASE-8 promoter was found in 11.8% of the normal ovary samples, 20% of the cystadenoma tumors and 20% of the metastatic EOC, while methylation of the CASPASE-8 promoter was absent in the EOC primary tissues (P=0.047). 24412083 2014
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer
0.020 GeneticVariation disease BEFREE Genetic variants of the CASP8 gene protect against EOC carcinogenesis and delay the age of EOC onset. 21714991 2011