AKT1S1, AKT1 substrate 1, 84335

N. diseases: 55; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE In addition, the functional role of key Akt pathway members such as PRAS40, GSK3 kinases, WEE1 kinase in melanoma development are discussed together with strategies to modulate these targets. 28064546 2017
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE PRAS40 plays an important role in metabolic disorders and multiple cancers, and the phosphorylation of PRAS40 is often associated with the tumor progression of melanoma, prostate cancer, etc. 28978182 2017
CUI: C0025202
Disease: melanoma
melanoma
0.040 AlteredExpression disease BEFREE Here PRAS40 overexpression in lung adenocarcinoma and cutaneous melanoma was significantly correlated to worse prognosis. 28945219 2017
CUI: C0025202
Disease: melanoma
melanoma
0.040 Biomarker disease BEFREE PRAS40 deregulates apoptosis in malignant melanoma. 17440074 2007