CDC14A, cell division cycle 14A, 8556

N. diseases: 26; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 GeneticVariation disease UNIPROT CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 CausalMutation disease CLINVAR CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 Biomarker disease CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 GeneticVariation disease CLINVAR CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 Biomarker disease GENOMICS_ENGLAND Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 Biomarker disease CTD_human Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 CausalMutation disease CLINVAR Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C1837608
Disease: DEAFNESS, AUTOSOMAL RECESSIVE 32
DEAFNESS, AUTOSOMAL RECESSIVE 32
0.700 GeneticVariation disease UNIPROT Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. 27259055 2016
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness
0.320 Biomarker disease CLINGEN CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness
0.320 GeneticVariation disease BEFREE Mutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35. 18179891 2008
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness
0.320 GeneticVariation disease BEFREE Mapping of a new autosomal recessive nonsyndromic hearing loss locus (DFNB32) to chromosome 1p13.3-22.1. 12634867 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 GeneticVariation disease BEFREE The CDC14A and MTMR3 mutations detected in the GC and CRC were deletion or duplication mutations of one base in the nucleotide repeats that would result in premature stops of the amino acid syntheses. 20477815 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 GeneticVariation disease UNIPROT
CUI: C0011052
Disease: Prelingual Deafness
Prelingual Deafness
0.300 Biomarker disease CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0011053
Disease: Deafness
Deafness
0.300 Biomarker phenotype CTD_human Auditory hair cells of postnatal Cdc14a mutants develop normally, but subsequently degenerate causing deafness. 29293958 2018
CUI: C0021364
Disease: Male infertility
Male infertility
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0028960
Disease: Oligospermia
Oligospermia
0.300 Biomarker disease CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0086395
Disease: Hearing Loss, Extreme
Hearing Loss, Extreme
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0581883
Disease: Complete Hearing Loss
Complete Hearing Loss
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0751068
Disease: Deafness, Acquired
Deafness, Acquired
0.300 Biomarker disease CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0848676
Disease: Subfertility, Male
Subfertility, Male
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0917731
Disease: Male sterility
Male sterility
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C3665473
Disease: Bilateral Deafness
Bilateral Deafness
0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C4082305
Disease: Deaf Mutism
Deaf Mutism
0.300 Biomarker disease CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.110 GeneticVariation disease GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017