Disease: Graves Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018213
Disease: Graves Disease
Graves Disease 		0.020 GeneticVariation disease BEFREE The HLA locus did not cosegregate with disease in DR3 positive families, suggesting that HLA genes are not major genes for AITD expression even within DR3 positive families; Hence, although HLA-DR3 was associated with GD in the probands, it was most likely a modulating gene and not causative; and, as the DR3 positive families showed evidence for linkage with D3S1580, it may imply that the DR3 gene modulated the effect of a susceptibility gene within the D3S1580 locus. 12100074 2002
CUI: C0018213
Disease: Graves Disease
Graves Disease 		0.020 Biomarker disease BEFREE Inheritance of Graves' disease has been linked to the HA-DR3 gene product which may function in some specific way in antigen presentation. 1617108 1992