|
Rheumatoid Arthritis
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
However, we did not find significant association between neither BANK1 rs3733197 polymorphism nor MMEL1/TNFRSF14 rs3890745 polymorphism and RA.
|
28925718 |
2017 |
|
Rheumatoid Arthritis
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Correction: The Expression of LIGHT Was Increased and the Expression of HVEM and BTLA Were Decreased in the T Cells of Patients with Rheumatoid Arthritis.
|
28253339 |
2017 |
|
Rheumatoid Arthritis
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
A series of bioinformatic analyses identified TNFRSF14-MMEL1 at the 1p36 locus and IKZF3-ORMDL3-GSDMB at the 17q12 locus as the genes most likely associated with RA.
|
22365150 |
2012 |
|
Rheumatoid Arthritis
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
TNFRSF6B and TNFRSF14 genes were recently associated with Crohn's disease and rheumatoid arthritis.
|
20962851 |
2011 |
|
Rheumatoid Arthritis
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the combined effect of the TNFRSF14 rs6684865 and TNFRSF6B rs4809330 polymorphisms in RA predisposition.
|
20187130 |
2010 |
|
Rheumatoid Arthritis
|
0.380 |
Biomarker
|
disease |
CTD_human |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
|
Rheumatoid Arthritis
|
0.380 |
Biomarker
|
disease |
BEFREE |
Herpesvirus entry mediator-Ig treatment during immunization aggravates rheumatoid arthritis in the collagen-induced arthritis model.
|
19234211 |
2009 |
|
Rheumatoid Arthritis
|
0.380 |
Biomarker
|
disease |
BEFREE |
To study the expression of LIGHT (tumor necrosis factor superfamily 14) and herpesvirus entry mediator (HVEM; tumor necrosis factor receptor superfamily 14) in rheumatoid arthritis (RA) and to determine the regulatory role of LIGHT on the effector functions of fibroblast-like synoviocytes (FLS).
|
17393389 |
2007 |
|
Rheumatoid Arthritis
|
0.380 |
AlteredExpression
|
disease |
LHGDN |
High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases.
|
14749527 |
2003 |
|
Lymphoma, Follicular
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
In the BCL-u group, TNFRSF14 mutations clustered with a FL immunophenotype.
|
27297871 |
2017 |
|
Lymphoma, Follicular
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
As lymphoma B cells can act as antigen-presenting cells, we hypothesized that TNFRSF14 aberrations that reduce HVEM expression could alter the capacity of FL B cells to stimulate allogeneic T-cell responses and impact the outcome of AHSCT.
|
27103745 |
2016 |
|
Lymphoma, Follicular
|
0.370 |
Biomarker
|
disease |
BEFREE |
Of the six cases lacking 1p36 deletion, TNFRSF14 mutations were identified in three, highlighting the strong association of 1p36/TNFRSF14 abnormalities with this follicular lymphoma variant.
|
26965583 |
2016 |
|
Lymphoma, Follicular
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The second most commonly mutated gene in PTNFL was TNFRSF14, with a mutation frequency of 29%, similar to that seen in limited-stage typical FL (P = .35).
|
27325104 |
2016 |
|
Lymphoma, Follicular
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Among the most notable alterations, we observed and validated deletions of 1p36 and gains of the 7p and 12q chromosomes and related oncogenes, which include some of the most recurrent oncogenic alterations in overt follicular lymphoma (TNFRSF14, EZH2, MLL2).
|
24162788 |
2014 |
|
Lymphoma, Follicular
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Recurrent loss of heterozygosity in 1p36 associated with TNFRSF14 mutations in IRF4 translocation negative pediatric follicular lymphomas.
|
23445872 |
2013 |
|
Lymphoma, Follicular
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis.
|
20884631 |
2010 |
|
Lymphoma, Follicular
|
0.370 |
CausalMutation
|
disease |
CGI |
|
|
|
|
Celiac Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
|
Myocardial Infarction
|
0.200 |
Biomarker
|
disease |
RGD |
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure.
|
18353719 |
2008 |
|
Ulcerative Colitis
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Ulcerative Colitis
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
We confirmed the associations of 10 known UC risk loci in Koreans: rs76418789 in IL23R (combined P = 1.25 × 10), rs4728142 in IRF5 (combined P = 3.17 × 10), rs1830610 near JAK2 (combined P = 2.28 × 10), rs1555791 near TNFRSF14 (combined P = 1.62 × 10), rs880790 between IL10-IL19 (combined P = 3.73 × 10), rs10185424 between IL1R2-IL1R1 (combined P = 1.54 × 10), rs6478108 in TNFSF15 (combined P = 9.28 × 10), rs861857 between UBE2L3-YDJC (combined P = 3.05 × 10), rs1801274 in FCGR2A (discovery P = 1.54 × 10), and rs17085007 between GPR12-USP12 (discovery P = 3.64 × 10).
|
26398853 |
2016 |
|
Crohn Disease
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Crohn Disease
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
TNFRSF6B and TNFRSF14 genes were recently associated with Crohn's disease and rheumatoid arthritis.
|
20962851 |
2011 |
|
Hypothyroidism
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Expression of HVEM was not associated with age, gender, administration of preoperative chemotherapy, tumor size, number of tumors, or histologic differentiation.
|
31313042 |
2019 |