WNT3A, Wnt family member 3A, 89780

N. diseases: 141; N. variants: 5
Disease: Anaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002793
Disease: Anaplasia
Anaplasia 		0.020 Biomarker disease BEFREE Differentiating 3T3-L1 fibroblasts into mature adipocytes produced striking increases in P2 gene-products and dramatic falls in P1-transcribed mRNA, whereas Wnt3a-induced dedifferentiation of mature adipocytes produced reciprocal changes in P1 and P2 transcript levels. 25024173 2014
CUI: C0002793
Disease: Anaplasia
Anaplasia 		0.020 Biomarker disease BEFREE We examined if mature adipocytes can also be target cells and found that canonical Wnt activation by Wnt3a induced a marked dedifferentiation of both 3T3-L1 and human adipocytes. 20179324 2010