CCNH, cyclin H, 902

N. diseases: 83; N. variants: 37
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 Biomarker disease BEFREE Among 8 fusion genes, MAN2A1-FER, TRMT11-GRIK2 and CCNH-C5orf30 appear most frequently in hepatocellular carcinoma samples. 31164957 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 Biomarker disease BEFREE The mycoplasmal membrane protein p37 showed significant correlations with higher histologic stages and vascular invasion and predicted poor disease-free survival of HCC patients. p37-positive CTCs were detected in 42 out of 47 HCC patients (89%). p37-positive circulating cells were also detected in 4 out of 10 healthy donors (40%), and all were epithelial cell adhesion molecule (EpCAM)-positive. 30980864 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 Biomarker disease BEFREE These results suggest that mycoplasma induces a resistance to multiple drugs in hepatocarcinoma cells which required the interaction of P37 and Annexin A2. 28976984 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.040 Biomarker disease BEFREE Previously, we generated 6 monoclonal antibodies (MAbs) against the mycoplasmal protein p37 and showed the presence of mycoplasma-infected circulating tumor cells in the blood of hepatocellular carcinoma patients by using CA27, one of the six MAbs. 28036384 2016