CD6, CD6 molecule, 923

N. diseases: 216; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.050 GeneticVariation disease BEFREE Differential expression of TCN1 (transcobalamin I), IFI44 (Interferon-induced protein 44), HMGB2 (high-mobility group box 2) and FUS [Fusion (involved in t(12;16) in malignant liposarcoma)] among other genes were further confirmed by western-blot and/or real-time polymerase chain reaction. 20042637 2010
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.050 Biomarker disease BEFREE This subtype of liposarcoma contains the specific t(12;16) chromosomal translocation, which results in rearrangement of the TLS and CHOP genes that is clone specific at the DNA level. 10914725 2000
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.050 GeneticVariation disease BEFREE Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t(12;6). 11126370 2000
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.050 Biomarker disease BEFREE Other cytogenetic findings of translocation t(12;16) indicate that round cell liposarcomas share chromosomal changes with myxoid liposarcomas, and further suggest that both tumor subtypes of liposarcoma may possess common precursor cells. 9103213 1997
CUI: C0023827
Disease: liposarcoma
liposarcoma
0.050 GeneticVariation disease BEFREE Localization of the chromosomal breakpoints of the t(12;16) in liposarcoma to subbands 12q13.3 and 16p11.2. 2372777 1990