Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
GDF-15 is induced in hypertrophic and dilated cardiomyopathy after volume overload, ischemia, and heart failure.
|
31663791 |
2020 |
Heart failure
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study we compared the plasma levels of NT-proBNP versus GDF-15 in patients with HF in AF versus sinus rhythm (SR).
|
31263996 |
2020 |
Congestive heart failure
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study we compared the plasma levels of NT-proBNP versus GDF-15 in patients with HF in AF versus sinus rhythm (SR).
|
31263996 |
2020 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
GDF-15 is induced in hypertrophic and dilated cardiomyopathy after volume overload, ischemia, and heart failure.
|
31663791 |
2020 |
Coronary Arteriosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Potential relation between soluble growth differentiation factor-15 and testosterone deficiency in male patients with coronary artery disease.
|
30819257 |
2019 |
Coronary Arteriosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
We conducted a Mendelian randomisation study to examine the role of GDF-15 in risk of coronary artery disease (CAD) and breast and colorectal cancer.
|
31161347 |
2019 |
Coronary Arteriosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Association of circulating growth differentiation factor-15, Krüppel-like factor 4 and growth arrest-specific 6 with coronary artery disease.
|
31153870 |
2019 |
Coronary Arteriosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Potential associations of circulating growth differentiation factor-15 with sex hormones in male patients with coronary artery disease.
|
30909145 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although, in general, effects of NRG-1 in heart failure are compensatory and beneficial, translation into therapies remains unaccomplished both because of the complexity of the underlying pathways and because of the challenges in the development of therapeutics (proteins, peptides, small molecules, and RNA-based therapies) for tyrosine kinase receptors.
|
31607147 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the setting of ACS, GDF-15 is associated with long-term all-cause death, MACE and heart failure and provides incremental prognostic value beyond traditional risks factor.
|
31369736 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Safety, Tolerability and efficacy of Rapid Optimization, helped by NT-proBNP and GDF-15, of Heart Failure therapies (STRONG-HF): rationale and design for a multicentre, randomized, parallel-group study.
|
31423712 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, we evaluated whether GDF-15 was associated with CV death or heart failure (HF) across the spectrum of risk in non-ST-segment elevation (NSTE)-ACS.
|
30710475 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.
|
30935637 |
2019 |
Heart failure
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We aimed to analyse the association between high-level growth-differentiation factor-15 (GDF-15) and mortality, recurrent MI and heart failure compared to low-level GDF-15 in patients with acute coronary syndrome (ACS).
|
31029521 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Higher NT-proBNP, hsTnT, and GDF-15 were also associated with a greater risk of HF with reduced EF; while higher NT-proBNP GDF-15 and sST2 were associated with HF with preserved EF.
|
31645163 |
2019 |
Heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
GDF-15, a member of the transforming growth factor beta superfamily, regulates inflammatory and apoptotic pathways in various diseases, such as heart failure, kidney dysfunction, and cancer.
|
31476622 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Safety, Tolerability and efficacy of Rapid Optimization, helped by NT-proBNP and GDF-15, of Heart Failure therapies (STRONG-HF): rationale and design for a multicentre, randomized, parallel-group study.
|
31423712 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, we evaluated whether GDF-15 was associated with CV death or heart failure (HF) across the spectrum of risk in non-ST-segment elevation (NSTE)-ACS.
|
30710475 |
2019 |
Congestive heart failure
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We aimed to analyse the association between high-level growth-differentiation factor-15 (GDF-15) and mortality, recurrent MI and heart failure compared to low-level GDF-15 in patients with acute coronary syndrome (ACS).
|
31029521 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although, in general, effects of NRG-1 in heart failure are compensatory and beneficial, translation into therapies remains unaccomplished both because of the complexity of the underlying pathways and because of the challenges in the development of therapeutics (proteins, peptides, small molecules, and RNA-based therapies) for tyrosine kinase receptors.
|
31607147 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
Higher NT-proBNP, hsTnT, and GDF-15 were also associated with a greater risk of HF with reduced EF; while higher NT-proBNP GDF-15 and sST2 were associated with HF with preserved EF.
|
31645163 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the setting of ACS, GDF-15 is associated with long-term all-cause death, MACE and heart failure and provides incremental prognostic value beyond traditional risks factor.
|
31369736 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.
|
30935637 |
2019 |
Congestive heart failure
|
0.400 |
Biomarker
|
disease |
BEFREE |
GDF-15, a member of the transforming growth factor beta superfamily, regulates inflammatory and apoptotic pathways in various diseases, such as heart failure, kidney dysfunction, and cancer.
|
31476622 |
2019 |
Neoplasm Metastasis
|
0.400 |
AlteredExpression
|
phenotype |
BEFREE |
Furthermore, ectopic expression of GDF15 can partially rescue TK1 knockdown-induced LUAD growth and metastasis inhibition, confirming its important role as a downstream mediator of TK1 function in LUAD.
|
31589613 |
2019 |