MFN2, mitofusin 2, 9927

N. diseases: 334; N. variants: 75
Disease: Cardiomegaly ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic phenotype RGD Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats. 27847271 2017
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker phenotype RGD Candesartan cilexetil attenuated cardiac remodeling by improving expression and function of mitofusin 2 in SHR. 27085127 2016
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker phenotype CTD_human Down-regulation of mitofusin-2 expression in cardiac hypertrophy in vitro and in vivo. 17499311 2007