MFN2, mitofusin 2, 9927

N. diseases: 334; N. variants: 75
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751651
Disease: Mitochondrial Diseases
Mitochondrial Diseases
0.030 Biomarker group BEFREE Collectively, these data identify the E2F1-MFN2 axis as a regulator of mitochondrial morphology and mitophagy, suggesting a potential therapeutic target for the treatment of mitochondrial disorders. 31276298 2019
CUI: C0751651
Disease: Mitochondrial Diseases
Mitochondrial Diseases
0.030 GeneticVariation group BEFREE Mutations within Mfn1 or Mfn2 impair mitochondrial fusion and lead to some severe mitochondrial dysfunctions and mitochondrial diseases (MDs). 31609634 2019
CUI: C0751651
Disease: Mitochondrial Diseases
Mitochondrial Diseases
0.030 Biomarker group BEFREE The widespread peripheral and CNS involvement, as well as the neurosensorial defects, underline the similarities among MFN2-related and primary mitochondrial disorders. 18946002 2008
CUI: C0751651
Disease: Mitochondrial Diseases
Mitochondrial Diseases
0.030 AlteredExpression group LHGDN The widespread peripheral and CNS involvement, as well as the neurosensorial defects, underline the similarities among MFN2-related and primary mitochondrial disorders. 18946002 2008