Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 AlteredExpression disease BEFREE In addition, evidence suggested that either miR-22 silencing or FXR knockdown reversed the diminished CCNA2 expression as well as cell proliferation inhibition caused by WA treatment and WA inhibited tumor masses in vivo in a subcutaneous xenograft mouse model of HCC. 27738335 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease CTD_human Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3. 25496033 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease BEFREE Aberrant DNA methylation of G-protein-coupled bile acid receptor Gpbar1 (TGR5) is a potential biomarker for hepatitis B Virus associated hepatocellular carcinoma. 24465162 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease CTD_human Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice. 23811326 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 AlteredExpression disease BEFREE In this study, we found that the expression of miR-421 was inversely correlated with FXR protein level in HCC cell lines. 22446874 2012
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease MGD Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. 17283114 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease MGD Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. 17183066 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.530 Biomarker disease MGD Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. 11030617 2000