Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
BEFREE |
This multicenter study evaluated the association of 9 single nucleotide polymorphisms (SNP) in AXIN2 and CDH1, representing genes consistently altered in breast and gastric tumors, with NSCL ± P in 223 trios (father, mother and patient with NSCL ± P) by transmission disequilibrium test (TDT).
|
28376813 |
2017 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
CTD_human |
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
|
24816253 |
2014 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
BEFREE |
Despite advances with traditional single genes molecular research, including rare mutations in BRCA1/2 and CDH1 for primary prevention and trastuzumab for treating HER2-overexpressing breast and gastric tumors, overall, treatment failure and death rates are still alarmingly high.
|
20975737 |
2011 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
CTD_human |
Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.
|
19184424 |
2010 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
CTD_human |
Germline CDH1 deletions in hereditary diffuse gastric cancer families.
|
19168852 |
2009 |
Stomach Neoplasms
|
0.600 |
AlteredExpression
|
group |
LHGDN |
The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers.
|
18427545 |
2008 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer.
|
18312357 |
2008 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
|
18482459 |
2008 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Hereditary diffuse gastric cancer: association with lobular breast cancer.
|
18046629 |
2008 |
Stomach Neoplasms
|
0.600 |
AlteredExpression
|
group |
LHGDN |
Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells.
|
18377425 |
2008 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
|
17545690 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
|
17852867 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population.
|
17549573 |
2007 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells.
|
17396032 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
E-cadherin and hereditary diffuse gastric cancer.
|
17981184 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Germline E-cadherin mutations in familial lobular breast cancer.
|
17660459 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family.
|
17126523 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
|
17221870 |
2007 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
|
16870389 |
2006 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
CDH1/E-cadherin germline mutations in early-onset gastric cancer.
|
16801346 |
2006 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin.
|
16132582 |
2005 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management.
|
16061854 |
2005 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
CDH1 associated gastric cancer: a report of a family and review of the literature.
|
15780560 |
2005 |
Stomach Neoplasms
|
0.600 |
Biomarker
|
group |
LHGDN |
Clinical significance of dysadherin expression in gastric cancer patients.
|
15102690 |
2004 |
Stomach Neoplasms
|
0.600 |
GeneticVariation
|
group |
LHGDN |
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
|
15235021 |
2004 |