|
Carcinoma, Lobular
|
0.690 |
GeneticVariation
|
disease |
BEFREE |
A 51- year old woman, with known CDH1 mutation carrier status and a prior history of lobular breast carcinoma underwent prophylactic total gastrectomy which revealed multifocal intramucosal signet ring cell carcinoma.
|
23849133 |
2013 |
|
Carcinoma, Lobular
|
0.690 |
AlteredExpression
|
disease |
BEFREE |
For instance, secretory carcinomas of the breast consistently harbour the t(12;15) translocation that leads to the formation of the ETV6-NTRK3 fusion gene, adenoid cystic carcinomas consistently display the t(6;9) MYB-NFIB translocation and lobular carcinomas consistently show inactivation of the CDH1 gene through multiple molecular mechanisms.
|
20452298 |
2010 |
|
Carcinoma, Lobular
|
0.690 |
GeneticVariation
|
disease |
LHGDN |
Hereditary diffuse gastric cancer: association with lobular breast cancer.
|
18046629 |
2008 |
|
Carcinoma, Lobular
|
0.690 |
Biomarker
|
disease |
CTD_human |
Germline E-cadherin mutations in familial lobular breast cancer.
|
17660459 |
2007 |
|
Carcinoma, Lobular
|
0.690 |
AlteredExpression
|
disease |
LHGDN |
In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin.
|
17437014 |
2007 |
|
Carcinoma, Lobular
|
0.690 |
Biomarker
|
disease |
LHGDN |
E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast.
|
15696125 |
2005 |
|
Carcinoma, Lobular
|
0.690 |
GeneticVariation
|
disease |
BEFREE |
Also, germline CDH1 mutations may predispose to lobular breast carcinoma and prostate cancer.
|
14630673 |
2003 |
|
Carcinoma, Lobular
|
0.690 |
AlteredExpression
|
disease |
BEFREE |
Frequent E-cadherin gene inactivation by loss of heterozygosity in pleomorphic lobular carcinoma of the breast.
|
12861063 |
2003 |
|
Carcinoma, Lobular
|
0.690 |
GeneticVariation
|
disease |
BEFREE |
Here we have analyzed the coding region of CDH1 for mutations using denaturing high performance liquid chromatography and found 4 mutations in 83 ductal carcinomas (5%) and 3 mutations in 25 lobular carcinomas (12%).
|
11857408 |
2002 |
|
Carcinoma, Lobular
|
0.690 |
AlteredExpression
|
disease |
BEFREE |
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast.
|
11291078 |
2001 |
|
Carcinoma, Lobular
|
0.690 |
Biomarker
|
disease |
CTD_human |
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.
|
8557030 |
1995 |
|
Carcinoma, Lobular
|
0.690 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Carcinoma, Lobular
|
0.690 |
CausalMutation
|
disease |
CGI |
|
|
|