DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.020 1.000 2 2012 2015
dbSNP: rs10063995
rs10063995 		1.000 0.040 5 175445201 upstream gene variant G/C;T snv
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs10078866
rs10078866 		1.000 0.080 5 175445317 upstream gene variant A/G snv 5.2E-02
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs10078866
rs10078866 		1.000 0.080 5 175445317 upstream gene variant A/G snv 5.2E-02
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2015 2015
dbSNP: rs155417
rs155417 		1.000 0.040 5 175441837 synonymous variant T/A;C snv 0.99
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs1799914
rs1799914 		1.000 0.040 5 175442902 synonymous variant C/T snv 8.2E-03 2.1E-03
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2010 2010
dbSNP: rs265981
rs265981 		0.925 0.080 5 175443899 5 prime UTR variant A/G;T snv
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 < 0.001 1 2015 2015
dbSNP: rs265981
rs265981 		0.925 0.080 5 175443899 5 prime UTR variant A/G;T snv
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs265981
rs265981 		0.925 0.080 5 175443899 5 prime UTR variant A/G;T snv
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2015 2015
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C3714760
Disease: Drug-induced tardive dyskinesia
Drug-induced tardive dyskinesia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders 0.010 1.000 1 2011 2011
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0686347
Disease: Tardive Dyskinesia
Tardive Dyskinesia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2011 2011
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		Cardiovascular Diseases 0.010 1.000 1 2016 2016
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2008 2008
dbSNP: rs4532
rs4532 		0.827 0.160 5 175443147 5 prime UTR variant C/T snv 0.68 0.72
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C0021122
Disease: Disruptive, Impulse Control, and Conduct Disorders
Disruptive, Impulse Control, and Conduct Disorders 		Mental Disorders 0.010 1.000 1 2018 2018
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C0853193
Disease: Bipolar I disorder
Bipolar I disorder 		Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 < 0.001 1 2015 2015
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C0686347
Disease: Tardive Dyskinesia
Tardive Dyskinesia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2011 2011
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C3714760
Disease: Drug-induced tardive dyskinesia
Drug-induced tardive dyskinesia 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders 0.010 1.000 1 2011 2011
dbSNP: rs5326
rs5326 		0.851 0.160 5 175443193 5 prime UTR variant C/T snv 0.15
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2015 2015
dbSNP: rs686
rs686 		0.807 0.080 5 175441697 3 prime UTR variant G/A;C;T snv
CUI: C0036572
Disease: Seizures
Seizures 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs686
rs686 		0.807 0.080 5 175441697 3 prime UTR variant G/A;C;T snv
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs686
rs686 		0.807 0.080 5 175441697 3 prime UTR variant G/A;C;T snv
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs686
rs686 		0.807 0.080 5 175441697 3 prime UTR variant G/A;C;T snv
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.010 1.000 1 2008 2008