KLK3, kallikrein related peptidase 3, 354

N. diseases: 358; N. variants: 19
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1058205
rs1058205 		0.925 0.080 19 50860142 3 prime UTR variant C/T snv 0.75 0.74
CUI: C0201544
Disease: Prostate specific antigen measurement
Prostate specific antigen measurement 		0.800 1.000 2 2010 2014
dbSNP: rs17632542
rs17632542 		0.925 0.080 19 50858501 missense variant T/C snv 5.5E-02 4.9E-02
CUI: C0201544
Disease: Prostate specific antigen measurement
Prostate specific antigen measurement 		0.800 1.000 2 2010 2017
dbSNP: rs17632542
rs17632542 		0.925 0.080 19 50858501 missense variant T/C snv 5.5E-02 4.9E-02
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.750 0.714 7 2011 2015
dbSNP: rs17632542
rs17632542 		0.925 0.080 19 50858501 missense variant T/C snv 5.5E-02 4.9E-02
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.750 0.667 6 2011 2015
dbSNP: rs1058205
rs1058205 		0.925 0.080 19 50860142 3 prime UTR variant C/T snv 0.75 0.74
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.720 1.000 3 2008 2018
dbSNP: rs62113212
rs62113212 		0.925 0.080 19 50857584 non coding transcript exon variant C/G;T snv
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.710 0.500 2 2011 2015
dbSNP: rs1061477
rs1061477 		1.000 0.080 19 50856840 intron variant T/C snv 0.42
CUI: C0004096
Disease: Asthma
Asthma 		Respiratory Tract Diseases; Immune System Diseases 0.700 1.000 1 2012 2012
dbSNP: rs61752561
rs61752561 		0.925 0.080 19 50858126 missense variant G/A snv 2.4E-02 2.5E-02
CUI: C0201544
Disease: Prostate specific antigen measurement
Prostate specific antigen measurement 		0.700 1.000 1 2017 2017
dbSNP: rs266882
rs266882 		0.925 0.080 19 50854757 upstream gene variant G/A snv 0.49
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.050 0.800 5 2006 2018
dbSNP: rs266882
rs266882 		0.925 0.080 19 50854757 upstream gene variant G/A snv 0.49
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.050 0.800 5 2006 2018
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.040 0.750 4 2000 2008
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.040 0.500 4 2001 2008
dbSNP: rs1058205
rs1058205 		0.925 0.080 19 50860142 3 prime UTR variant C/T snv 0.75 0.74
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2017 2018
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C1704272
Disease: Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia 		Male Urogenital Diseases 0.020 0.500 2 2002 2005
dbSNP: rs149709822
rs149709822 		0.882 0.080 19 50856335 missense variant G/A snv 4.0E-05 2.3E-04
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.020 1.000 2 2000 2008
dbSNP: rs61752561
rs61752561 		0.925 0.080 19 50858126 missense variant G/A snv 2.4E-02 2.5E-02
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2010 2019
dbSNP: rs61752561
rs61752561 		0.925 0.080 19 50858126 missense variant G/A snv 2.4E-02 2.5E-02
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2010 2019
dbSNP: rs746367915
rs746367915 		0.925 0.080 19 50860089 missense variant C/T snv 8.0E-06 2.8E-05
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2005 2010
dbSNP: rs746367915
rs746367915 		0.925 0.080 19 50860089 missense variant C/T snv 8.0E-06 2.8E-05
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 1.000 2 2005 2010
dbSNP: rs1053972
rs1053972 		1.000 0.040 19 50855373 3 prime UTR variant C/T snv 0.24
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		Mental Disorders 0.010 1.000 1 2016 2016
dbSNP: rs1192131078
rs1192131078 		0.925 0.080 19 50858075 missense variant G/A snv 4.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1192131078
rs1192131078 		0.925 0.080 19 50858075 missense variant G/A snv 4.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1325243071
rs1325243071 		1.000 0.120 19 50858291 missense variant T/C snv
CUI: C0878773
Disease: Overactive Bladder
Overactive Bladder 		Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.010 1.000 1 2013 2013
dbSNP: rs141576693
rs141576693 		0.925 0.080 19 50856263 missense variant C/T snv 8.0E-05 2.8E-04
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2013 2013
dbSNP: rs141576693
rs141576693 		0.925 0.080 19 50856263 missense variant C/T snv 8.0E-05 2.8E-04
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2013 2013