TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C4086152
Disease: Childhood Astrocytoma
Childhood Astrocytoma 		Neoplasms 0.010 1.000 1 2002 2002
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		Neoplasms; Nervous System Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		Neoplasms 0.010 1.000 1 2002 2002
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2006 2006
dbSNP: rs11196205
rs11196205 		0.827 0.200 10 113047288 intron variant G/A;C;T snv
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2007 2007
dbSNP: rs1225404
rs1225404 		0.882 0.160 10 113154906 intron variant C/T snv 0.71
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2007 2007
dbSNP: rs1427214163
rs1427214163 		1.000 0.080 10 113151879 missense variant C/T snv 7.0E-06
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.010 < 0.001 1 2007 2007
dbSNP: rs7100927
rs7100927 		0.925 0.080 10 113036289 intron variant A/G snv 0.54
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 1.000 1 2007 2007
dbSNP: rs7100927
rs7100927 		0.925 0.080 10 113036289 intron variant A/G snv 0.54
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2007 2007
dbSNP: rs7100927
rs7100927 		0.925 0.080 10 113036289 intron variant A/G snv 0.54
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.700 1.000 1 2007 2007
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2007 2007
dbSNP: rs7900150
rs7900150 		0.882 0.160 10 113034064 intron variant T/A;C snv 0.54
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.700 1.000 1 2007 2007
dbSNP: rs3814573
rs3814573 		1.000 0.080 10 113138334 intron variant T/C snv 0.71
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.020 1.000 2 2007 2008
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2008 2008
dbSNP: rs11196205
rs11196205 		0.827 0.200 10 113047288 intron variant G/A;C;T snv
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs11196205
rs11196205 		0.827 0.200 10 113047288 intron variant G/A;C;T snv
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 1.000 1 2008 2008
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0020474
Disease: Hyperlipidemia, Familial Combined
Hyperlipidemia, Familial Combined 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1427214163
rs1427214163 		1.000 0.080 10 113151879 missense variant C/T snv 7.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs148523217
rs148523217 		1.000 0.080 10 113146030 missense variant C/A snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs4918789
rs4918789 		1.000 0.080 10 113062048 intron variant T/G snv 0.53
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2008 2008
dbSNP: rs557826746
rs557826746 		1.000 0.080 10 112950901 missense variant G/C snv 4.0E-06
CUI: C1842402
Disease: TROPICAL CALCIFIC PANCREATITIS
TROPICAL CALCIFIC PANCREATITIS 		Digestive System Diseases; Nutritional and Metabolic Diseases 0.010 1.000 1 2008 2008
dbSNP: rs77961654
rs77961654 		1.000 0.080 10 113165610 missense variant C/A snv 5.3E-02 2.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 < 0.001 1 2008 2008
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		Cardiovascular Diseases 0.010 < 0.001 1 2008 2008