TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C4086152
Disease: Childhood Astrocytoma
Childhood Astrocytoma 		Neoplasms 0.010 1.000 1 2002 2002
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		Neoplasms; Nervous System Diseases 0.010 < 0.001 1 2002 2002
dbSNP: rs766727892
rs766727892 		0.925 0.040 10 113151107 missense variant G/A snv 1.2E-05 7.0E-06
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		Neoplasms 0.010 1.000 1 2002 2002
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.900 0.953 190 2006 2020
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.900 0.908 65 2006 2020
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 1.000 37 2006 2020
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.100 1.000 35 2006 2020
dbSNP: rs7901695
rs7901695 		0.851 0.160 10 112994329 intron variant T/C snv 0.34
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.900 1.000 23 2006 2020
dbSNP: rs11196205
rs11196205 		0.827 0.200 10 113047288 intron variant G/A;C;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.800 0.917 12 2006 2020
dbSNP: rs4506565
rs4506565 		0.790 0.280 10 112996282 intron variant A/G;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.870 0.900 10 2006 2020
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.090 1.000 9 2006 2016
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0011847
Disease: Diabetes
Diabetes 		Endocrine System Diseases 0.090 1.000 9 2006 2016
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		Nutritional and Metabolic Diseases 0.070 1.000 7 2006 2020
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		Nutritional and Metabolic Diseases 0.040 0.750 4 2006 2017
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance 		Nutritional and Metabolic Diseases 0.030 1.000 3 2006 2011
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2006 2006
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.100 0.944 18 2007 2019
dbSNP: rs290487
rs290487 		0.776 0.280 10 113149972 intron variant C/T snv 0.16
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 0.667 15 2007 2015
dbSNP: rs11196218
rs11196218 		0.925 0.160 10 113080735 intron variant G/A snv 0.25
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.100 0.700 10 2007 2015
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.090 0.444 9 2007 2017
dbSNP: rs12255372
rs12255372 		0.667 0.480 10 113049143 intron variant G/A;T snv
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes 		Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.070 0.857 7 2007 2019
dbSNP: rs10885409
rs10885409 		1.000 0.080 10 113048313 intron variant T/C snv 0.54
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.720 1.000 4 2007 2015
dbSNP: rs7895340
rs7895340 		0.851 0.160 10 113041766 intron variant G/A snv 0.53
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.040 0.500 4 2007 2013
dbSNP: rs7903146
rs7903146 		0.554 0.680 10 112998590 intron variant C/G;T snv
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.040 0.750 4 2007 2019
dbSNP: rs3814573
rs3814573 		1.000 0.080 10 113138334 intron variant T/C snv 0.71
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.020 1.000 2 2007 2008