rs114951929
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Smoking Behaviors
0.700
GeneticVariation
GWASCAT
Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
26053186
2015
rs114951929
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Smoking
0.700
GeneticVariation
GWASCAT
Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
26053186
2015
rs112384084
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Parkinson Disease
T
0.700
GeneticVariation
CLINVAR
rs113498671
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Ovarian Mucinous Adenocarcinoma
0.700
GeneticVariation
UNIPROT
rs970946035
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Endometrioid carcinoma ovary
0.700
GeneticVariation
UNIPROT
rs201768983
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Endometrial Carcinoma
0.010
GeneticVariation
BEFREE
The TNK2(P761Rfs*72) frameshift mutation was recurrent in EC , and the DDR1(R570Q ) missense mutation was recurrent across tumor types.
25427824
2014
rs201768983
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Malignant neoplasm of endometrium
0.010
GeneticVariation
BEFREE
The TNK2(P761Rfs*72) frameshift mutation was recurrent in EC , and the DDR1(R570Q ) missense mutation was recurrent across tumor types.
25427824
2014
rs2278034
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Hepatitis C
0.010
GeneticVariation
BEFREE
SNP rs2278034 in ACK1 is associated with IFN therapy outcome in patients with HCV .
21129804
2011
rs970946035
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Primary malignant neoplasm
0.010
GeneticVariation
BEFREE
Thus, the cancer -associated mutation E346K appears to destabilize an autoinhibited conformation of Ack1, leading to constitutively high Ack1 activity.
20110370
2010
rs970946035
×
Entrez Id:
10188
Gene Symbol:
TNK2
TNK2
Malignant Neoplasms
0.010
GeneticVariation
BEFREE
Thus, the cancer -associated mutation E346K appears to destabilize an autoinhibited conformation of Ack1, leading to constitutively high Ack1 activity.
20110370
2010