CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2395655
rs2395655
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs3176336
rs3176336
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0023508
Disease:
White Blood Cell Count procedure
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2395655
rs2395655
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0202236
Disease:
Triglycerides measurement
A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs3176326
rs3176326
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0004238
Disease:
Atrial Fibrillation
G 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
dbSNP: rs3176326
rs3176326
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0004238
Disease:
Atrial Fibrillation
G 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs762624
rs762624
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0004238
Disease:
Atrial Fibrillation
A 0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study for atrial fibrillation. 29892015 2018
dbSNP: rs762624
rs762624
Entrez Id: 1026;108783646
Gene Symbol: CDKN1A;DINOL
CDKN1A;DINOL
CUI: C0948008
Disease:
Ischemic stroke
A 0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
dbSNP: rs3829964
rs3829964
Entrez Id: 1026;101154753
Gene Symbol: CDKN1A;PANDAR
CDKN1A;PANDAR
CUI: C0678222
Disease:
Breast Carcinoma
C 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
dbSNP: rs3176353
rs3176353
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1445957
Disease:
Serum total cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs3176353
rs3176353
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0202236
Disease:
Triglycerides measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE And larger scale primary studies are required to further evaluate the interaction of p21 3' UTR rs1059234 polymorphism and cancer risk in specific populations. 26278624 2015
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE And larger scale primary studies are required to further evaluate the interaction of p21 3' UTR rs1059234 polymorphism and cancer risk in specific populations. 26278624 2015
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Thus, larger scale primary studies are still required to further evaluate the interaction of p21 rs1059234 polymorphism and cancer risk in specific cancer subtypes. 26028110 2015
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Thus, larger scale primary studies are still required to further evaluate the interaction of p21 rs1059234 polymorphism and cancer risk in specific cancer subtypes. 26028110 2015
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) of p53 rs1042522, MDM2 rs2279744 and p21 rs1801270, all in the p53 pathway, which plays a crucial role in DNA damage and genomic instability, were reported to be associated with cancer risk and pathologic characteristics. 26289323 2015
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) of p53 rs1042522, MDM2 rs2279744 and p21 rs1801270, all in the p53 pathway, which plays a crucial role in DNA damage and genomic instability, were reported to be associated with cancer risk and pathologic characteristics. 26289323 2015
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Although many epidemiological studies have been conducted to evaluate the association between the p21 Ser31Arg polymorphism and cancer risk, the findings remain conflicting. 21439247 2011
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Although many epidemiological studies have been conducted to evaluate the association between the p21 Ser31Arg polymorphism and cancer risk, the findings remain conflicting. 21439247 2011
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Two polymorphisms of p21 gene in codon 31 (p21 C98A, dbSNP rs1801270) and the 3'UTR (p21 C70T, dbSNP rs1059234) may affect protein expression and play a role in cancer susceptibility. 20433229 2010
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Two polymorphisms of p21 gene in codon 31 (p21 C98A, dbSNP rs1801270) and the 3'UTR (p21 C70T, dbSNP rs1059234) may affect protein expression and play a role in cancer susceptibility. 20433229 2010
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Two polymorphisms of p21 gene in codon 31 (p21 C98A, dbSNP rs1801270) and the 3'UTR (p21 C70T, dbSNP rs1059234) may affect protein expression and play a role in cancer susceptibility. 20433229 2010
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Two polymorphisms of p21 gene in codon 31 (p21 C98A, dbSNP rs1801270) and the 3'UTR (p21 C70T, dbSNP rs1059234) may affect protein expression and play a role in cancer susceptibility. 20433229 2010
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Two polymorphisms of the p21 gene at codon 31 (p21 C98A, dbSNP rs1801270) and at the 3' untranslated region (p21 T70C, dbSNP rs1059234) may have an effect on the protein function and may thus play a role in the development of cancer. 15878916 2005
dbSNP: rs1059234
rs1059234
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0006826
Disease:
Malignant Neoplasms
0.040 GeneticVariation BEFREE Two polymorphisms of the p21 gene at codon 31 (p21 C98A, dbSNP rs1801270) and at the 3' untranslated region (p21 T70C, dbSNP rs1059234) may have an effect on the protein function and may thus play a role in the development of cancer. 15878916 2005
dbSNP: rs1801270
rs1801270
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C1306459
Disease:
Primary malignant neoplasm
0.040 GeneticVariation BEFREE Two polymorphisms of the p21 gene at codon 31 (p21 C98A, dbSNP rs1801270) and at the 3' untranslated region (p21 T70C, dbSNP rs1059234) may have an effect on the protein function and may thus play a role in the development of cancer. 15878916 2005