rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
BEFREE
(2) Four additional AD risk SNPs were nominally associated with obesity (rs17125944 at FERMT2, pBMI = 4.03 × 10(-05), pBMI corr = 2.50 × 10(-03) ; rs3851179 at PICALM; pBMI = 0.002, rs2075650 at TOMM40/APOE, pBMI = 0.024, rs3865444 at CD33, pBMI = 0.024).
24788522
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Obesity
0.010
GeneticVariation
BEFREE
(2) Four additional AD risk SNPs were nominally associated with obesity (rs17125944 at FERMT2, pBMI = 4.03 × 10(-05), pBMI corr = 2.50 × 10(-03) ; rs3851179 at PICALM; pBMI = 0.002, rs2075650 at TOMM40/APOE, pBMI = 0.024, rs3865444 at CD33, pBMI = 0.024).
24788522
2014
rs1160985
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Low density lipoprotein cholesterol measurement
T
0.800
GeneticVariation
GWASCAT
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
24386095
2013
rs1160985
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Serum total cholesterol measurement
T
0.800
GeneticVariation
GWASDB
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
24386095
2013
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Mental deterioration
G
0.800
GeneticVariation
GWASDB
A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
23207651
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Mental deterioration
G
0.800
GeneticVariation
GWASCAT
A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
23207651
2014
rs8106922
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Low density lipoprotein cholesterol measurement
A
0.800
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs1038026
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
High density lipoprotein measurement
A
0.700
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs1038026
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Low density lipoprotein cholesterol measurement
A
0.700
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs157588
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
High density lipoprotein measurement
C
0.700
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs157588
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Low density lipoprotein cholesterol measurement
C
0.700
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs8106922
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Serum total cholesterol measurement
A
0.700
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Body mass index
A
0.700
GeneticVariation
GWASCAT
A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.
30108127
2018
rs10524523
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.100
GeneticVariation
BEFREE
A number of recent studies have not replicated the association of the translocase of the outer mitochondrial membrane pore subunit (TOMM40) rs10524523 polymorphism, which is in linkage disequilibrium with apolipoprotein E (APOE), with age of onset of Alzheimer's disease (AD ).
23333464
2013
rs10524523
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer Disease, Late Onset
0.080
GeneticVariation
BEFREE
A variable poly-T length polymorphism at rs10524523 , within intron 6 of the translocase of the outer mitochondrial membrane (TOMM40) gene, has been shown to influence age of onset in LOAD , with very long (VL) poly-T length associated with earlier disease onset, and short poly-T length associated with later onset.
21784354
2011
rs10524523
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer Disease, Late Onset
0.080
GeneticVariation
BEFREE
A variable-length poly-T variant in intron 6 of the TOMM40 gene, rs10524523 , is associated with risk and age-of-onset of sporadic (late-onset) Alzheimer's disease .
28768149
2017
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASDB
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.900
GeneticVariation
GWASCAT
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs11556505
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.700
GeneticVariation
GWASDB
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs34404554
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.700
GeneticVariation
GWASDB
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
24770881
2014
rs157580
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
0.810
GeneticVariation
BEFREE
Alleles A of CD33 rs3865444 and A of TOMM40 rs157580 were both protective factors for AD onset (OR=0.94, 95% CI: 0.9 0-0.98, P value=0.003; OR=0.62, 95% CI: 0.57-0.66, P value <0.001).
26795201
2016
rs59007384
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
Alzheimer's Disease
T
0.700
GeneticVariation
GWASCAT
APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.
23419831
2014
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
C-reactive protein measurement
G
0.800
GeneticVariation
GWASCAT
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
23844046
2013
rs2075650
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
C-reactive protein measurement
G
0.800
GeneticVariation
GWASDB
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
23844046
2013
rs10119
×
Entrez Id:
10452
Gene Symbol:
TOMM40
TOMM40
C-reactive protein measurement
G
0.700
GeneticVariation
GWASDB
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
23844046
2013