CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1800947
rs1800947
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
C 0.800 GeneticVariation GWASCAT Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. 30388399 2018
dbSNP: rs3091244
rs3091244
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
A 0.800 GeneticVariation GWASCAT Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. 30388399 2018
dbSNP: rs1800947
rs1800947
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291 2013
dbSNP: rs3091244
rs3091244
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291 2013
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291 2013
dbSNP: rs3091244
rs3091244
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASDB Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
G 0.800 GeneticVariation GWASCAT Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. 21196492 2011
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
G 0.800 GeneticVariation GWASDB Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. 21196492 2011
dbSNP: rs3091244
rs3091244
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASCAT Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. 18439548 2008
dbSNP: rs3091244
rs3091244
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.800 GeneticVariation GWASDB Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. 18439548 2008
dbSNP: rs1205
rs1205
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
C 0.700 GeneticVariation GWASDB New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis. 24763700 2014
dbSNP: rs1130864
rs1130864
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291 2013
dbSNP: rs1205
rs1205
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
T 0.700 GeneticVariation GWASDB Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 23844046 2013
dbSNP: rs1205
rs1205
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291 2013
dbSNP: rs1205
rs1205
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs1205
rs1205
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. 22291609 2012
dbSNP: rs3093058
rs3093058
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0201657
Disease:
C-reactive protein measurement
0.700 GeneticVariation GWASDB C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans. 22492993 2012
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0004096
Disease:
Asthma
0.700 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864 2011
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.050 GeneticVariation BEFREE The adjusted odds ratios (ORs) [95% confidence interval (95% CI)] of IS per addition of the modelled allele were 1.07 (0.79-1.45) for rs876537, 0.99 (0.73-1.35) for rs1205 and 1.08 (0.71-1.65) for rs3093059. 31692152 2020
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.050 GeneticVariation BEFREE Two SNPs, rs30</span>93059 (dominant model: adjusted OR 2.49; 95% CI 1.55-4.00; recessive model: adjusted OR 3.67; 95</span>% CI 1.22-11.03) and rs11265260 (dominant model: adjusted OR 2.51; 95% CI 1.56-4.02; recessive model: adjusted OR 4.70; 95% CI 1.63-13.56) independently predicted 3-month poor outcome of first-ever LAA IS, after adjusting for covariates. 29556980 2018
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.050 GeneticVariation BEFREE We found that rs2794521, rs3093059, and rs1205 were associated with decreased IS risk; we also found that gene-gene interaction between rs2794521 and rs3093059, and gene-environment interaction between rs2794521 and smoking were associated with decreased IS risk. 28287042 2017
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.050 GeneticVariation BEFREE No association was found between the rs3093059 and ischaemic stroke. 26004291 2015
dbSNP: rs3093059
rs3093059
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.050 GeneticVariation BEFREE The results indicated that rs3093059 and rs3091244 presented statistical associations with ischemic stroke. 22875596 2013
dbSNP: rs1800947
rs1800947
Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0948008
Disease:
Ischemic stroke
0.040 GeneticVariation BEFREE <b>Results</b>: Three out of 10 eligible SNPs were shown to be associated with risk of ischemic stroke. rs1800947 in <i>CRP</i> gene (additive model: OR = 2.08, 95% CI: 1.00-4.23) and rs1169288 in <i>HNF1A</i> gene (additive model: OR = 1.45, 95% CI: 1.03-2.06) were associated with an increased risk of ischemic stroke. rs440446 in <i>APOE</i> gene (additive model: OR = 0.63, 95%CI: 0.44-0.88) was associated with a decreased risk of ischemic stroke. 31584351 2019