CTBP2, C-terminal binding protein 2, 1488

N. diseases: 62; N. variants: 13
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0600139
Disease:
Prostate carcinoma
C 0.720 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016 2018
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0600139
Disease:
Prostate carcinoma
0.720 GeneticVariation BEFREE Our results suggest that rs4962416, previously associated only with prostate cancer, is also associated with PSA levels, with 12% increase for each copy of the minor allele C. The study enabled the replication of the effect for the majority of previously reported genetic variants in a set of clinically relevant prostate cancers. 26773531 2016
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.720 GeneticVariation BEFREE Our results suggest that rs4962416, previously associated only with prostate cancer, is also associated with PSA levels, with 12% increase for each copy of the minor allele C. The study enabled the replication of the effect for the majority of previously reported genetic variants in a set of clinically relevant prostate cancers. 26773531 2016
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0600139
Disease:
Prostate carcinoma
0.720 GeneticVariation BEFREE After allowing for multiple testing, none of the SNPs examined were significantly associated with growth factor or hormone concentrations, and the SNP-prostate cancer associations did not differ by these concentrations, although 4 interactions were marginally significant (MSMB-rs10993994 with androstenedione (uncorrected P = 0.008); CTBP2-rs4962416 with IGFBP-3 (uncorrected P = 0.003); 11q13.2-rs12418451 with IGF-1 (uncorrected P = 0.006); and 11q13.2-rs10896449 with SHBG (uncorrected P = 0.005)). 22459122 2012
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
0.720 GeneticVariation BEFREE After allowing for multiple testing, none of the SNPs examined were significantly associated with growth factor or hormone concentrations, and the SNP-prostate cancer associations did not differ by these concentrations, although 4 interactions were marginally significant (MSMB-rs10993994 with androstenedione (uncorrected P = 0.008); CTBP2-rs4962416 with IGFBP-3 (uncorrected P = 0.003); 11q13.2-rs12418451 with IGF-1 (uncorrected P = 0.006); and 11q13.2-rs10896449 with SHBG (uncorrected P = 0.005)). 22459122 2012
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0376358
Disease:
Malignant neoplasm of prostate
C 0.720 GeneticVariation GWASDB Multiple loci identified in a genome-wide association study of prostate cancer. 18264096 2008
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0600139
Disease:
Prostate carcinoma
C 0.720 GeneticVariation GWASCAT Multiple loci identified in a genome-wide association study of prostate cancer. 18264096 2008
dbSNP: rs10901868
rs10901868
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1561589
rs1561589
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1305855
Disease:
Body mass index
A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs2919290
rs2919290
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1314691
Disease:
Age at menarche
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs35106605
rs35106605
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0014772
Disease:
Red Blood Cell Count measurement
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs4021186
rs4021186
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1314691
Disease:
Age at menarche
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1561589
rs1561589
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1305855
Disease:
Body mass index
G 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs2946994
rs2946994
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1305855
Disease:
Body mass index
G 0.700 GeneticVariation GWASCAT Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. 29273807 2018
dbSNP: rs3781411
rs3781411
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C4049938
Disease:
Physical Activity Measurement
C 0.700 GeneticVariation GWASCAT Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. 29899525 2018
dbSNP: rs4411245
rs4411245
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0428883
Disease:
Diastolic blood pressure
A 0.700 GeneticVariation GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018
dbSNP: rs57592469
rs57592469
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0596887
Disease:
mathematical ability
A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs3781426
rs3781426
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C0005890
Disease:
Body Height
T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. 25429064 2015
dbSNP: rs718948
rs718948
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT Genetic studies of body mass index yield new insights for obesity biology. 25673413 2015
dbSNP: rs1915146
rs1915146
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C1314691
Disease:
Age at menarche
G 0.700 GeneticVariation GWASCAT Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. 25231870 2014
dbSNP: rs4962416
rs4962416
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
CUI: C2931822
Disease:
Nasopharyngeal carcinoma
0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010