RASGRP3, RAS guanyl releasing protein 3, 25780

N. diseases: 34; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.810 GeneticVariation GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.810 GeneticVariation GWASCAT Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. 26663301 2016
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.810 GeneticVariation BEFREE Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively. 20516000 2010
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.810 GeneticVariation GWASCAT Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.810 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs17013215
rs17013215
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs17013215
rs17013215
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		C 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs2305573
rs2305573
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs7565568
rs7565568
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs2124437
rs2124437
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0220641
Disease:
Lip and Oral Cavity Carcinoma 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0042384
Disease:
Vasculitis 		0.010 GeneticVariation BEFREE Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively. 20516000 2010
dbSNP: rs13385731
rs13385731
Entrez Id: 25780
Gene Symbol: RASGRP3
RASGRP3
CUI: C0027697
Disease:
Nephritis 		0.010 GeneticVariation BEFREE Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively. 20516000 2010