rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
BEFREE |
The HLA-DRB1 rs660895 showed both wild (AA) and heterozygote (AG) genotype but the heterozygote allele was found to be associated with reduced risk of RA compared to controls [OR = 0.531, p = .024].
|
29168332 |
2018 |
rs660895
|
HLA-DRB1
|
IGA Glomerulonephritis
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Identification of new susceptibility loci for IgA nephropathy in Han Chinese.
|
26028593 |
2015 |
rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
G |
0.810 |
GeneticVariation |
GWASCAT |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
rs660895
|
HLA-DRB1
|
IGA Glomerulonephritis
|
G |
0.810 |
GeneticVariation |
GWASDB |
We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047).
|
22197929 |
2011 |
rs660895
|
HLA-DRB1
|
IGA Glomerulonephritis
|
G |
0.810 |
GeneticVariation |
GWASCAT |
We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047).
|
22197929 |
2011 |
rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
rs660895
|
HLA-DRB1
|
IGA Glomerulonephritis
|
|
0.810 |
GeneticVariation |
BEFREE |
We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047).
|
22197929 |
2011 |
rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
rs660895
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
GWASCAT |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
rs477515
|
HLA-DRB1
|
Epstein-Barr Virus Infections
|
T |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
|
23326239 |
2013 |
rs477515
|
HLA-DRB1
|
Epstein-Barr Virus Infections
|
T |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).
|
23326239 |
2013 |
rs9270984
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
rs9270984
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
T |
0.800 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
rs9271100
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
|
0.800 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
rs615672
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
rs9271100
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
|
19838193 |
2009 |
rs9271100
|
HLA-DRB1
|
Lupus Erythematosus, Systemic
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
|
19838193 |
2009 |
rs477515
|
HLA-DRB1
|
Inflammatory Bowel Diseases
|
|
0.800 |
GeneticVariation |
GWASDB |
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.
|
18758464 |
2008 |
rs477515
|
HLA-DRB1
|
Inflammatory Bowel Diseases
|
|
0.800 |
GeneticVariation |
GWASCAT |
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.
|
18758464 |
2008 |
rs615672
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
rs615672
|
HLA-DRB1
|
Rheumatoid Arthritis
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
rs2516049
|
HLA-DRB1
|
Crohn Disease
|
|
0.710 |
GeneticVariation |
BEFREE |
Of these, rs2516049 (closest gene HLA-DRB5; conjunction false discovery rate P = .04 for AD and psoriasis, 5.37 × 10-5 for AD, and 6.03 × 10-15 for psoriasis) and rs12570088 (closest gene IPMK; conjunction false discovery rate P = .009 for AD and Crohn disease, P = 5.73 × 10-6 for AD, and 6.57 × 10-5 for Crohn disease) demonstrated the same direction of allelic effect between AD and the immune-mediated diseases.
|
27088644 |
2016 |
rs3021304
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
G |
0.710 |
GeneticVariation |
GWASCAT |
We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).
|
25108386 |
2014 |
rs3021304
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
|
0.710 |
GeneticVariation |
BEFREE |
We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).
|
25108386 |
2014 |