IL10, interleukin 10, 3586

N. diseases: 1679; N. variants: 21
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3024493
rs3024493
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs1800872
rs1800872
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE The anti-inflammatory genes, haem oxygenase 1 (HO-1, HMOX1) rs2071746 (unrestricted model: p = 9.07 × 10-4; recessive model: p = 4.99 × 10-4; multiplicative model: p = 0.0009; and additive model: p = 1.87 × 10-4) and interleukin-10 (IL-10) rs1800872 (dominant model: p = 0.0277) have been associated with paediatric inflammatory bowel disease. 28770550 2017
dbSNP: rs1800872
rs1800872
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE The results showed that IL-10 rs304496 was associated with pediatric IBD (<i>P</i> = 0.022), but no association was found for two other IL-10 SNPs, rs1800872 and rs2034498, or for SNPs in genes <i>IL10RA</i>, <i>IL10RB</i>, <i>STAT3</i>, and <i>HO1</i>. 28785144 2017
dbSNP: rs1800896
rs1800896
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE A total of 101 patients diagnosed with inflammatory bowel disease were analysed for the tumour necrosis factor-alpha (-308 G/A; rs1800629) and interleukin-10 (-1082 G/A; rs1800896) gene polymorphisms. 27528546 2016
dbSNP: rs1800872
rs1800872
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE To assess the relationship of the Interleukin-10 (IL-10) -1082G/A (rs1800896), -819C/T (rs1800871) and -592C/A (rs1800872) polymorphism with inflammatory bowel disease (IBD) by means of meta-analysis. 24128120 2014
dbSNP: rs1800896
rs1800896
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE To understand how turmeric may influence the consequences of a genetic predisposition to inappropriate inflammation, we used HEK293 cells to examine the in vitro capacity of turmeric extract and fractions to affect the functionality of two gene variants, solute carrier protein 22 A4 (SLC22A4, rs1050152) and interleukin-10 (IL-10, rs1800896) associated with IBD. 25314644 2014
dbSNP: rs1800896
rs1800896
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.030 GeneticVariation BEFREE To assess the relationship of the Interleukin-10 (IL-10) -1082G/A (rs1800896), -819C/T (rs1800871) and -592C/A (rs1800872) polymorphism with inflammatory bowel disease (IBD) by means of meta-analysis. 24128120 2014
dbSNP: rs1800871
rs1800871
Entrez Id: 3586;29949
Gene Symbol: IL10;IL19
IL10;IL19
CUI: C0021390
Disease:
Inflammatory Bowel Diseases
0.010 GeneticVariation BEFREE To assess the relationship of the Interleukin-10 (IL-10) -1082G/A (rs1800896), -819C/T (rs1800871) and -592C/A (rs1800872) polymorphism with inflammatory bowel disease (IBD) by means of meta-analysis. 24128120 2014