|
rs582537
|
IL12A;IL12A-AS1
|
Primary biliary cirrhosis
|
|
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.
|
28425483 |
2017 |
|
rs582537
|
IL12A;IL12A-AS1
|
Primary biliary cirrhosis
|
|
0.800 |
GeneticVariation |
GWASDB |
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.
|
22961000 |
2012 |
|
rs2243112
|
IL12A;IL12A-AS1
|
Low density lipoprotein cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs2243112
|
IL12A;IL12A-AS1
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs2243112
|
IL12A;IL12A-AS1
|
Serum total cholesterol measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs582054
|
IL12A;IL12A-AS1
|
Primary biliary cirrhosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.
|
22961000 |
2012 |
|
rs647801
|
IL12A;IL12A-AS1
|
Primary biliary cirrhosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.
|
22961000 |
2012 |
|
rs2243115
|
IL12A;IL12A-AS1
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation |
BEFREE |
IL-12A polymorphisms (rs2243115 and rs568408) were found no influence on overall cancer risk.
|
28415696 |
2017 |
|
rs2243115
|
IL12A;IL12A-AS1
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation |
BEFREE |
IL-12A polymorphisms (rs2243115 and rs568408) were found no influence on overall cancer risk.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation |
BEFREE |
Nevertheless, stratification analyses demonstrated that rs568408 polymorphism contributed to increasing cancer risk of Caucasians and cervical cancer.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation |
BEFREE |
Nevertheless, stratification analyses demonstrated that rs568408 polymorphism contributed to increasing cancer risk of Caucasians and cervical cancer.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Cervix carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
Nevertheless, stratification analyses demonstrated that rs568408 polymorphism contributed to increasing cancer risk of Caucasians and cervical cancer.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Malignant tumor of cervix
|
|
0.030 |
GeneticVariation |
BEFREE |
Nevertheless, stratification analyses demonstrated that rs568408 polymorphism contributed to increasing cancer risk of Caucasians and cervical cancer.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Hodgkin Disease
|
|
0.030 |
GeneticVariation |
BEFREE |
Polymorphisms of IFNL3 rs8099917 and IL12A rs568408 contribute to survival of HD patients, but not as independent factors.
|
28525983 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
cervical cancer
|
|
0.030 |
GeneticVariation |
BEFREE |
Nevertheless, stratification analyses demonstrated that rs568408 polymorphism contributed to increasing cancer risk of Caucasians and cervical cancer.
|
28415696 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Huntington Disease
|
|
0.030 |
GeneticVariation |
BEFREE |
Polymorphisms of IFNL3 rs8099917 and IL12A rs568408 contribute to survival of HD patients, but not as independent factors.
|
28525983 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Liver carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
Our findings showed that IL12A rs568408 (G>A) polymorphism may contribute to the risk of HCC on top of chronic HCV infection, whereas that of IL12B rs3212227 (A>C) do not.
|
27819525 |
2017 |
|
rs568408
|
IL12A;IL12A-AS1
|
Liver carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results reveal that the IL12A rs568408 variant may be a marker SNP for risk of both HBV clearance and HBV-related HCC development.
|
26631030 |
2016 |
|
rs568408
|
IL12A;IL12A-AS1
|
Huntington Disease
|
|
0.030 |
GeneticVariation |
BEFREE |
The IL-12A rs568408 and IL-12B rs3212227 polymorphisms were analyzed in relation to anti-HBs development in 602 HD patients with negative antibodies to HBV core antigen (anti-HBc) who were hepatitis B vaccinated (group I) as well as in 237 anti-HBc positive HD patients who were infected with HBV in the past (group II).
|
24158609 |
2013 |
|
rs568408
|
IL12A;IL12A-AS1
|
Hodgkin Disease
|
|
0.030 |
GeneticVariation |
BEFREE |
The IL-12A rs568408 and IL-12B rs3212227 polymorphisms were analyzed in relation to anti-HBs development in 602 HD patients with negative antibodies to HBV core antigen (anti-HBc) who were hepatitis B vaccinated (group I) as well as in 237 anti-HBc positive HD patients who were infected with HBV in the past (group II).
|
24158609 |
2013 |
|
rs2243115
|
IL12A;IL12A-AS1
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation |
BEFREE |
However, the 3'UTR G>A (rs568408), IVS2 T>A (rs582054) and 5'UTR T>G (rs2243115) polymorphisms of IL-12A gene did not appear to have an influence on cancer susceptibility.
|
22940148 |
2012 |
|
rs2243115
|
IL12A;IL12A-AS1
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation |
BEFREE |
However, the 3'UTR G>A (rs568408), IVS2 T>A (rs582054) and 5'UTR T>G (rs2243115) polymorphisms of IL-12A gene did not appear to have an influence on cancer susceptibility.
|
22940148 |
2012 |
|
rs568408
|
IL12A;IL12A-AS1
|
Cervix carcinoma
|
|
0.030 |
GeneticVariation |
BEFREE |
We studied the contribution of the IL12A 3'UTR G>A (rs568408) and IL12B 3'UTR A>C (rs3212227) polymorphisms to the risk of cervical cancer.
|
22614250 |
2012 |
|
rs568408
|
IL12A;IL12A-AS1
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation |
BEFREE |
However, the 3'UTR G>A (rs568408), IVS2 T>A (rs582054) and 5'UTR T>G (rs2243115) polymorphisms of IL-12A gene did not appear to have an influence on cancer susceptibility.
|
22940148 |
2012 |
|
rs568408
|
IL12A;IL12A-AS1
|
Hodgkin Disease
|
|
0.030 |
GeneticVariation |
BEFREE |
In the logistic regression analysis, the higher frequency of rs360719 CC individually (2.9% in 207 patients without anti-HBs development vs 8.0% in 311 patients with anti-HBs development, p = 0.009) and of rs360719 CC combined with rs568408 GG (p = 0.048), rs568408 GA (p = 0.035), rs568408 GG/AA (p = 0.034) or rs3212227 AA (p = 0.046) was associated with an increased chance for the development of anti-HBs in HD patients.
|
22863216 |
2012 |