IL13, interleukin 13, 3596

N. diseases: 587; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE In contrast, the lack of any association between rs20541 (IL13) and psoriasis in our Egyptian cohort suggests the existence of important inter-ethnic genetic differences in psoriasis susceptibility. 25406098 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
G 0.860 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
G 0.860 GeneticVariation GWASCAT Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. 26626624 2015
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE In subgroup analyses, the two SNPs were significantly associated (P < 0.05) with type I psoriasis, Rs495337 showed statistically difference between positive family history of psoriasis patients and controls whereas rs20541 might preferentially associated with negative family history psoriasis patients. 23617596 2013
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear. 22286212 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE The minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis. 22694930 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). 21613309 2011
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation GWASDB Association analyses identify six new psoriasis susceptibility loci in the Chinese population. 20953187 2010
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
G 0.860 GeneticVariation GWASDB Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254 2009
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
G 0.860 GeneticVariation GWASCAT Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254 2009
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0033860
Disease:
Psoriasis
0.860 GeneticVariation BEFREE A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis. 18075513 2008
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation BEFREE IL-13 minor T and A alleles for rs1295686 and rs20541, respectively, were associated with significantly higher risk of asthma in the Saudi Arabian population. 29211635 2018
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation BEFREE IL13_rs1295686 was associated with all asthma (OR 1.64, 95% CI 1.16-2.32) and early-onset asthma (OR 1.92, 95% CI 1.20-3.06) in adults, whereas GSDMB_rs2305480 was only associated with early-onset asthma (OR 0.69, 95% CI 0.49-0.96). 26534891 2016
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation BEFREE We conducted an association study by genotyping four SNPs (rs2244012 and rs6871536 in RAD50 as well as rs1295686 and rs1800925 in IL13) in 652 asthmatic children and age-matched 752 healthy controls from Northeastern Han Chinese to evaluate the asthma susceptibility with each individual SNP using SNaPshot genotyping method. 26365633 2016
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation BEFREE There are controversies on the association between interleukin-13 (IL-13) +1923C/T polymorphism (rs1295686) and the risk of asthma. 23841068 2013
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531 2012
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.840 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864 2011
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
T 0.840 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
dbSNP: rs1295686
rs1295686
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
T 0.840 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0019829
Disease:
Hodgkin Disease
A 0.810 GeneticVariation GWASDB A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus. 24920014 2014
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0019829
Disease:
Hodgkin Disease
0.810 GeneticVariation BEFREE We searched for an association between the interleukin 4 receptor gene (IL4R) rs1805015 and interleukin 13 gene (IL13) rs20541 polymorphisms and the development of antibodies to hepatitis B surface antigen (anti-HBs) in the case of hepatitis B virus (HBV) vaccination or infection in hemodialysis (HD) patients. 23462527 2013
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0019829
Disease:
Hodgkin Disease
0.810 GeneticVariation GWASDB Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups. 22286212 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0019829
Disease:
Hodgkin Disease
0.810 GeneticVariation GWASCAT Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups. 22286212 2012
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
G 0.800 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806 2018
dbSNP: rs20541
rs20541
Entrez Id: 3596;101927761
Gene Symbol: IL13;TH2LCRR
IL13;TH2LCRR
CUI: C0004096
Disease:
Asthma
0.800 GeneticVariation BEFREE These results support the existence of a significant association between GSTP1 rs1695 and IL13 rs20541 SNPs, with susceptibility to asthma, in the population studied. 27561723 2018