rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
In contrast, the lack of any association between rs20541 (IL13) and psoriasis in our Egyptian cohort suggests the existence of important inter-ethnic genetic differences in psoriasis susceptibility.
|
25406098 |
2015 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
G |
0.860 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
|
25903422 |
2015 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
G |
0.860 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
In subgroup analyses, the two SNPs were significantly associated (P < 0.05) with type I psoriasis, Rs495337 showed statistically difference between positive family history of psoriasis patients and controls whereas rs20541 might preferentially associated with negative family history psoriasis patients.
|
23617596 |
2013 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear.
|
22286212 |
2012 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
The minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis.
|
22694930 |
2012 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs).
|
21613309 |
2011 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
G |
0.860 |
GeneticVariation |
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
G |
0.860 |
GeneticVariation |
GWASCAT |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
rs20541
|
IL13;TH2LCRR
|
Psoriasis
|
|
0.860 |
GeneticVariation |
BEFREE |
A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis.
|
18075513 |
2008 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
IL-13 minor T and A alleles for rs1295686 and rs20541, respectively, were associated with significantly higher risk of asthma in the Saudi Arabian population.
|
29211635 |
2018 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
IL13_rs1295686 was associated with all asthma (OR 1.64, 95% CI 1.16-2.32) and early-onset asthma (OR 1.92, 95% CI 1.20-3.06) in adults, whereas GSDMB_rs2305480 was only associated with early-onset asthma (OR 0.69, 95% CI 0.49-0.96).
|
26534891 |
2016 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
We conducted an association study by genotyping four SNPs (rs2244012 and rs6871536 in RAD50 as well as rs1295686 and rs1800925 in IL13) in 652 asthmatic children and age-matched 752 healthy controls from Northeastern Han Chinese to evaluate the asthma susceptibility with each individual SNP using SNaPshot genotyping method.
|
26365633 |
2016 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
BEFREE |
There are controversies on the association between interleukin-13 (IL-13) +1923C/T polymorphism (rs1295686) and the risk of asthma.
|
23841068 |
2013 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
GWASDB |
Genome-wide association study to identify genetic determinants of severe asthma.
|
22561531 |
2012 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
|
0.840 |
GeneticVariation |
GWASDB |
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.
|
21907864 |
2011 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
T |
0.840 |
GeneticVariation |
GWASDB |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
rs1295686
|
IL13;TH2LCRR
|
Asthma
|
T |
0.840 |
GeneticVariation |
GWASCAT |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
rs20541
|
IL13;TH2LCRR
|
Hodgkin Disease
|
A |
0.810 |
GeneticVariation |
GWASDB |
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
|
24920014 |
2014 |
rs20541
|
IL13;TH2LCRR
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation |
BEFREE |
We searched for an association between the interleukin 4 receptor gene (IL4R) rs1805015 and interleukin 13 gene (IL13) rs20541 polymorphisms and the development of antibodies to hepatitis B surface antigen (anti-HBs) in the case of hepatitis B virus (HBV) vaccination or infection in hemodialysis (HD) patients.
|
23462527 |
2013 |
rs20541
|
IL13;TH2LCRR
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation |
GWASDB |
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.
|
22286212 |
2012 |
rs20541
|
IL13;TH2LCRR
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation |
GWASCAT |
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.
|
22286212 |
2012 |
rs20541
|
IL13;TH2LCRR
|
Asthma
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
|
29273806 |
2018 |
rs20541
|
IL13;TH2LCRR
|
Asthma
|
|
0.800 |
GeneticVariation |
BEFREE |
These results support the existence of a significant association between GSTP1 rs1695 and IL13 rs20541 SNPs, with susceptibility to asthma, in the population studied.
|
27561723 |
2018 |